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IPR001229 is a Jacalin-like lectin domain.
<p>The jacalin-like mannose-binding lectin domain has a β-prism fold consisting of three 4-stranded β-sheets, with an internal pseudo 3-fold symmetry. Some proteins with this domain stimulate distinct T- and B- cell functions, such as the plant lectin jacalin, which binds to the T-antigen and acts as an agglutinin. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. While the family was initially named after an abundant protein found in the jackfruit seed, taxonomic distribution is not restricted to plants. The domain is also found in the salt-stress induced protein from rice and an animal prostatic spermine-binding protein. Proteins containing this domain include:</p> <ul> <li>Jacalin, a tetrameric plant seed lectin and agglutinin from Artocarpus heterophyllus (jackfruit), which is specific for galactose [[cite:PUB00013978]].</li> <li>Artocarpin, a tetrameric plant seed lectin from A. heterophyllus [[cite:PUB00022824]].</li> <li>Lectin MPA, a tetrameric plant seed lectin and agglutinin from Maclura pomifera (Osage orange), [[cite:PUB00026468]].</li> <li>Heltuba lectin, a plant seed lectin and agglutinin from Helianthus tuberosus (Jerusalem artichoke) [[cite:PUB00023843]].</li> <li>Agglutinin from Calystegia sepium (Hedge bindweed) [[cite:PUB00029602]].</li> <li>Griffithsin, an anti-viral lectin from red algae (Griffithsia species) [[cite:PUB00041180]].</li> </ul>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: agglutinin-like [Glycine max] gi|356569525|ref|XP_003552950.1| | 10 | ||
| – | Myrosinase-binding protein-like protein [Medicago truncatula] gi|357490819|ref|XP_003615697.1| | 10 | ||
| – | Agglutinin alpha chain [Medicago truncatula] gi|357454743|ref|XP_003597652.1| | 10 | ||
| – | Agglutinin alpha chain [Medicago truncatula] gi|357454743|ref|XP_003597652.1| | 10 | ||
| – | Jacalin lectin family protein; TAIR: AT1G19715.1 Mannose-binding lectin superfamily protein; Swiss-Prot: sp|F4HQX1|JAL3_ARATH Jacalin-related lectin 3; TrEMBL-Plants: tr|G7JZI6|G7JZI6_MEDTR Mannose-binding lectin superfamily protein; Found in the gene: LotjaGi1g1v0119300 | 11 | ||
| – | Jacalin lectin family protein; TAIR: AT1G19715.1 Mannose-binding lectin superfamily protein; Swiss-Prot: sp|F4HQX1|JAL3_ARATH Jacalin-related lectin 3; TrEMBL-Plants: tr|A0A0B2RMC1|A0A0B2RMC1_GLYSO Agglutinin; Found in the gene: LotjaGi6g1v0123300 | 11 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd09612 | CDD | 1 | 16.67 |