Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message

IPR002504

Description

IPR002504 is a NAD kinase.

<p>Members of this family are NAD kinases [ec:2.7.1.23]. The enzymes catalyse the phosphorylation of NAD to NADP utilizing ATP and other nucleoside triphosphates, as well as inorganic polyphosphate, as a source of phosphorus. Such enzymes are thus designated poly(P)/ATP-NAD kinases [[cite:PUB00027720]]. NAD kinase is one of the key enzymes regulating the cellular NADP(H) level, and therefore NADPH-dependent reductive biosynthetic pathways [[cite:PUB00070138]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
Molecular function NAD+ kinase activity Catalysis of the reaction: ATP + NAD(+) = ADP + 2 H(+) + NADP(+).
Biological process NADP biosynthetic process The chemical reactions and pathways resulting in the formation of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; biosynthesis may be of either the oxidized form, NADP, or the reduced form, NADPH.

Associated Lotus transcripts 14

Transcript Name Description Predicted domains Domain count
PREDICTED: NADH kinase-like [Cicer arietinum] gi|502089692|ref|XP_004488989.1| 8
PREDICTED: NADH kinase-like [Cicer arietinum] gi|502089692|ref|XP_004488989.1| 16
PREDICTED: NAD kinase 2, chloroplastic-like [Glycine max] gi|356515937|ref|XP_003526653.1| 22
PREDICTED: NAD(H) kinase 1-like [Glycine max] gi|356538479|ref|XP_003537731.1| 10
PREDICTED: NAD kinase 2, chloroplastic-like [Glycine max] gi|356552711|ref|XP_003544706.1| 15
NAD kinase; TAIR: AT1G21640.1 NAD kinase 2; Swiss-Prot: sp|Q9C5W3|NADK2_ARATH NAD kinase 2, chloroplastic; TrEMBL-Plants: tr|K7M700|K7M700_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0157200 15
NAD kinase; TAIR: AT1G21640.1 NAD kinase 2; Swiss-Prot: sp|Q9C5W3|NADK2_ARATH NAD kinase 2, chloroplastic; TrEMBL-Plants: tr|I1KAE3|I1KAE3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0266100 23
NAD kinase; TAIR: AT1G78590.1 NAD(H) kinase 3; Swiss-Prot: sp|Q500Y9|NADHK_ARATH NADH kinase; TrEMBL-Plants: tr|A0A151QWC5|A0A151QWC5_CAJCA NADH kinase; Found in the gene: LotjaGi3g1v0257800_LC 14
NAD kinase; TAIR: AT1G78590.1 NAD(H) kinase 3; Swiss-Prot: sp|Q500Y9|NADHK_ARATH NADH kinase; TrEMBL-Plants: tr|A0A072VK73|A0A072VK73_MEDTR NAD/NADH kinase family protein; Found in the gene: LotjaGi3g1v0257800_LC 8
NAD kinase; TAIR: AT1G78590.1 NAD(H) kinase 3; Swiss-Prot: sp|Q500Y9|NADHK_ARATH NADH kinase; TrEMBL-Plants: tr|A0A072VK73|A0A072VK73_MEDTR NAD/NADH kinase family protein; Found in the gene: LotjaGi3g1v0257800_LC 8
NAD kinase; TAIR: AT1G78590.1 NAD(H) kinase 3; Swiss-Prot: sp|Q500Y9|NADHK_ARATH NADH kinase; TrEMBL-Plants: tr|A0A072VK73|A0A072VK73_MEDTR NAD/NADH kinase family protein; Found in the gene: LotjaGi3g1v0257800_LC 8
NAD kinase; TAIR: AT1G78590.1 NAD(H) kinase 3; Swiss-Prot: sp|Q500Y9|NADHK_ARATH NADH kinase; TrEMBL-Plants: tr|A0A072VK73|A0A072VK73_MEDTR NAD/NADH kinase family protein; Found in the gene: LotjaGi3g1v0304000 16
NAD kinase; TAIR: AT3G21070.2 NAD kinase 1; Swiss-Prot: sp|Q56YN3|NADK1_ARATH NAD(H) kinase 1; TrEMBL-Plants: tr|K7LNT1|K7LNT1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0536700 12
NAD kinase; TAIR: AT3G21070.2 NAD kinase 1; Swiss-Prot: sp|Q56YN3|NADK1_ARATH NAD(H) kinase 1; TrEMBL-Plants: tr|A0A0B2PCW9|A0A0B2PCW9_GLYSO NAD(H) kinase 1; Found in the gene: LotjaGi3g1v0536700 12

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 7.14