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IPR002882 is a 2-phospho-L-lactate transferase CofD.
<p>This entry contains 2-phospho-L-lactate transferase (CofD), phosphoenolpyruvate transferase and related sequences. CofD catalyses the fourth step in the biosynthesis of coenzyme F420, which is the transfer of the 2-phospholactate moiety from lactyl (2) diphospho-(5') guanosine (LPPG) to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) and GMP. F420 is a flavin derivative found in methanogens, Mycobacteria, and several other lineages. This enzyme is characterised so far in Methanocaldococcus jannaschii (Methanococcus jannaschii) [[cite:PUB00013496], [cite:PUB00050875]] but appears restricted to F420-containing species and is predicted to carry out the same function in these other species. CofD monomer contains twelve β-strands, seven of them forming a Rossmann fold, and thirteen α-helices [[cite:PUB00050875]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Maternal effect embryo arrest 18 [Theobroma cacao] gi|508780779|gb|EOY28035.1| | 9 | ||
| – | Maternal effect embryo arrest 18 [Theobroma cacao] gi|508780779|gb|EOY28035.1| | 9 | ||
| – | Maternal effect embryo arrest 18 protein; TAIR: AT2G34090.1 maternal effect embryo arrest 18; Swiss-Prot: sp|P53980|YNB1_YEAST Uncharacterized protein YNL011C; TrEMBL-Plants: tr|G7ILI7|G7ILI7_MEDTR Maternal effect embryo arrest 18 protein; Found in the gene: LotjaGi6g1v0323900 | 8 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd07187 | CDD | 1 | 33.33 |