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IPR004552

Source: InterPro

Description

IPR004552 is a 1-acyl-sn-glycerol-3-phosphate acyltransferase.

<p>This domain describes the core homologous region of a collection of related proteins, several of which are known to act as 1-acyl-sn-glycerol-3-phosphate acyltransferases ([ec:2.3.1.51]). Proteins scoring above the trusted cut-off are likely to have the same general activity, which is to convert acyl-CoA and 1-acyl-SN-glycerol 3-phosphate to CoA and 1,2-diacyl-SN-glycerol 3-phosphate. However, there is variation among characterised members as to whether the acyl group can be donated by acyl carrier protein or coenzyme A, and in the length and saturation of the donated acyl group [[cite:PUB00092800], [cite:PUB00057466], [cite:PUB00092801]]. 1-acyl-sn-glycerol-3-phosphate acyltransferase is also called 1-AGP acyltransferase, lysophosphatidic acid acyltransferase, and LPA acyltransferase.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0003841
Molecular function 1-acylglycerol-3-phosphate O-acyltransferase activity Catalysis of the reaction: acyl-CoA + 1-acyl-sn-glycerol-3-phosphate = CoA + 1,2-diacyl-sn-glycerol-3-phosphate.
Subterm of
GO:0008654
Biological process Phospholipid biosynthetic process The chemical reactions and pathways resulting in the formation of phospholipids, any lipid containing phosphoric acid as a mono- or diester.
Subterm of
GO:0016020
Cellular component Membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
Subterm of

Associated Lotus transcripts 1

Transcript Name Description Predicted domains Domain count
Lj6g3v1077830.1
– PREDICTED: 1-acyl-sn-glycerol-3-phosphate acyltransferase 1, chloroplastic-like [Glycine max] gi|356543360|ref|XP_003540129.1|
Domains
13

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd07989 CDD 1 100.00