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IPR004888 is a Glycoside hydrolase family 63.
<p>O-Glycosyl hydrolases ([ec:3.2.1.]) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families [[cite:PUB00004870], [cite:PUB00005266]]. This classification is available on the CAZy (CArbohydrate-Active EnZymes) website.</p> <p>This family of enzymes belongs to glycosyl hydrolase family 63 ([cazy:GH63]). They catalyse the specific cleavage of the non-reducing terminal glucose residue from Glc(3)Man(9)GlcNAc(2). Mannosyl oligosaccharide glucosidase [ec:3.2.1.106] is the first enzyme in the N-linked oligosaccharide processing pathway.</p> <p>This family also includes glucosylglycerate hydrolase which catalyses the hydrolysis of glucosylglycerate to glycerate and glucose, during the mycobacterial recovery from nitrogen starvation. This process promotes the rapid mobilisation of the glucosylglycerate that accumulates under these conditions. This enzyme can also hydrolyse mannosylglycerate with lower efficiency [[cite:PUB00094228]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Mannosyl-oligosaccharide glucosidase activity | Catalysis of the exohydrolysis of the non-reducing terminal glucose residue in the mannosyl-oligosaccharide Glc(3)Man(9)GlcNAc(2). | ||
| Biological process | Oligosaccharide metabolic process | The chemical reactions and pathways involving oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: mannosyl-oligosaccharide glucosidase GCS1-like [Cicer arietinum] gi|502141120|ref|XP_004504454.1| | 7 | ||
| – | PREDICTED: mannosyl-oligosaccharide glucosidase GCS1-like [Cicer arietinum] gi|502141120|ref|XP_004504454.1| | 7 | ||
| – | Mannosyl-oligosaccharide glucosidase; TAIR: AT1G67490.1 glucosidase 1; Swiss-Prot: sp|F4HTM3|GCS1_ARATH Mannosyl-oligosaccharide glucosidase GCS1; TrEMBL-Plants: tr|A0A072TT32|A0A072TT32_MEDTR Mannosyl-oligosaccharide glucosidase; Found in the gene: LotjaGi4g1v0364200 | 18 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 33.33 |