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IPR005218 is a Diacylglycerol/lipid kinase.
<p>This protein family include proteins predominantly from bacteria but also from some archaeal and eukaryotic species.</p> <p>The Escherichia coli member of this family, YegS, has been purified and shown to have phosphatidylglycerol kinase activity [[cite:PUB00039707]]. DagK from Bacillus subtilis catalyses the phosphorylation of diacylglycerol (DAG) into phosphatidic acid. It is a key enzyme involved in the production of lipoteichoic acid by reintroducing DAG formed from the breakdown of membrane phospholipids into the phosphatidylglycerol biosynthetic pathway. It is more active toward long-chain DAG compared with short-chain DAG and is not able to phosphorylate substrates other than DAG, such as monoacylglycerol, ceramide, undecaprenol, phosphatidylinositol, or sphingosine [[cite:PUB00053893]].</p> <p>Sphingoid long-chain bases kinase 2, mitochondrial from Arabidopsis thaliana (Mouse-ear cress) is involved in the production of sphingoid long-chain base (LCB). This protein is required for the cold-induced accumulation of phytosphingosine-phosphate, the regulation of the cold-responsive MPK6 and reduction of root growth at moderate low temperature [[cite:PUB00099966]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: diacylglycerol kinase-like [Cicer arietinum] gi|502105428|ref|XP_004492803.1| | 12 | ||
| – | Diacylglycerol kinase; TAIR: AT2G46090.1 Diacylglycerol kinase family protein; Swiss-Prot: sp|O82359|LCKB2_ARATH Sphingoid long-chain bases kinase 2, mitochondrial; TrEMBL-Plants: tr|G7L6P0|G7L6P0_MEDTR YegS/Rv2252/BmrU family lipid kinase; Found in the gene: LotjaGi1g1v0481600 | 13 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| TIGR00147 | TIGRFAM | 1 | 50.00 |