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IPR005689

Source: InterPro

Description

IPR005689 is a Chloroplast envelope protein translocase, IAP75.

<p>Chloroplast function requires the import of nuclear encoded proteins from the cytoplasm across the chloroplast double membrane. This is accompished by two protein complexes, the Toc complex located at the outer membrane and the Tic complex loacted at the inner membrane [[cite:PUB00034696]]. The Toc complex recognises specific proteins by a cleavable N-terminal sequence and is primarily responsible for translocation through the outer membrane, while the Tic complex translocates the protein through the inner membrane.</p> <p>This entry represents Toc750, a core component of the Toc complex. This protein is deeply embedded in the outer membrane and forms the voltage-dependent translocation channel [[cite:PUB00034698]]. Toc75 itself appears to be capable of at least some discrimination between substrate and non-substrate proteins, with recognition based on based on both conformational and electrostatic interactions.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0006886
Biological process Intracellular protein transport The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.
Subterm of
Part of
GO:0015450
Molecular function P-P-bond-hydrolysis-driven protein transmembrane transporter activity Primary active carrier-mediated transport of a protein across a membrane, driven by the hydrolysis of the diphosphate bond of inorganic pyrophosphate, ATP, or another nucleoside triphosphate. The transport protein may or may not be transiently phosphorylated, but the substrate is not phosphorylated.
Subterm of

Associated Lotus transcripts 1

Transcript Name Description Predicted domains Domain count
LotjaGi3g1v0285600.1
– Chloroplastic outer envelope membrane protein, putative, expressed; TAIR: AT3G46740.1 translocon at the outer envelope membrane of chloroplasts 75-III; Swiss-Prot: sp|Q43715|TOC75_PEA Protein TOC75, chloroplastic; TrEMBL-Plants: tr|A0A0L9UN31|A0A0L9UN31_PHAAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0285600
Domains
10

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 100.00