Description

IPR005845 is a Alpha-D-phosphohexomutase, alpha/beta/alpha domain II.

<p>This entry represents domain II found in alpha-D-phosphohexomutase enzymes. This domain has a 3-layer α/β/α topology.</p> <p>The alpha-D-phosphohexomutase superfamily is composed of four related enzymes, each of which catalyses a phosphoryl transfer on their sugar substrates: phosphoglucomutase (PGM), phosphoglucomutase/phosphomannomutase (PGM/PMM), phosphoglucosamine mutase (PNGM), and phosphoacetylglucosamine mutase (PAGM) [[cite:PUB00042561]]. PGM ([ec:5.4.2.2]) converts D-glucose 1-phosphate into D-glucose 6-phosphate, and participates in both the breakdown and synthesis of glucose [[cite:PUB00037156]]. PGM/PMM ([ec:5.4.2.2]; [ec:5.4.2.8]) are primarily bacterial enzymes that use either glucose or mannose as substrate, participating in the biosynthesis of a variety of carbohydrates such as lipopolysaccharides and alginate [[cite:PUB00040705], [cite:PUB00022429]]. Both PNGM ([ec:5.4.2.3]) and PAGM ([ec:5.4.2.10]) are involved in the biosynthesis of UDP-N-acetylglucosamine [[cite:PUB00042562], [cite:PUB00042563]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on April 27, 2020, while the GO metadata was last updated on April 27, 2020.

Associated Lotus transcripts 26

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space: