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IPR006434 is a Pyrimidine 5'-nucleotidase, eukaryotic.
<p>This family is a small group of metazoan sequences with sequences from Arabidopsis thaliana (Mouse-ear cress) and rice. The sequences represent pyrimidine 5-nucleotidases, apparently in reference to HSPC233, the Homo sapiens (Human) homologue [[cite:PUB00055591]]. The structure of mouse sequence has been reported [[cite:PUB00039616]]. This group of sequences was originally found during searches for members of the haloacid dehalogenase (HAD) superfamily. All of the conserved catalytic motifs [[cite:PUB00003337]] are found. The placement of the variable domain between motifs 1 and 2 indicates membership in subfamily I of the superfamily, but these sequences are sufficiently different from any of the branches of that subfamily (IA-ID) as to constitute a separate branch to now be called IE. Considering that the closest identifiable hit outside of the noise range is to a phosphoserine phosphatase, this group may be considered to be most closely allied to subfamily IB.</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Magnesium ion binding | Interacting selectively and non-covalently with magnesium (Mg) ions. | ||
| Cellular component | Cytoplasm | All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. | ||
| Molecular function | 5'-nucleotidase activity | Catalysis of the reaction: a 5'-ribonucleotide + H2O = a ribonucleoside + phosphate. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: cytosolic 5'-nucleotidase 3-like [Glycine max] gi|356576391|ref|XP_003556315.1| | 7 | ||
| – | PREDICTED: cytosolic 5'-nucleotidase 3-like [Glycine max] gi|356576391|ref|XP_003556315.1| | 7 | ||
| – | PREDICTED: cytosolic 5'-nucleotidase 3-like [Glycine max] gi|356576391|ref|XP_003556315.1| | 7 | ||
| – | Cytosolic 5-nucleotidase; TAIR: AT2G38680.1 5'-nucleotidase / magnesium ion binding protein; Swiss-Prot: sp|Q9D020|5NT3A_MOUSE Cytosolic 5'-nucleotidase 3A; TrEMBL-Plants: tr|I1NHU7|I1NHU7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0256100 | 11 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| SSF56784 | SUPERFAMILY | 1 | 25.00 |