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IPR006578 is a MADF domain.
<p>The MADF (myb/SANT-like domain in Adf-1) domain is an approximately 80-amino-acid module that directs sequence specific DNA binding to a site consisting of multiple tri-nucleotide repeats. The MADF domain is found in one or more copies in eukaryotic and viral proteins and is often associated with the BESS domain [[cite:PUB00018479]]. MADF is related to the Myb DNA-binding domain ([interpro:IPR001005]). The retroviral oncogene v-myb, and its cellular counterpart c-myb, are nuclear DNA-binding proteins that specifically recognise the sequence YAAC(G/T)G. It is likely that the MADF domain is more closely related to the myb/SANT domain than it is to other HTH domains. Some proteins known to contain a MADF domain are listed below:</p> <ul><li>Drosophila Adf-1, a transcription factor first identified on the basis of its interaction with the alcohol dehydrogenase promoter but that binds the promoters of a diverse group of genes [[cite:PUB00018477]].</li> <li>Drosophila Dorsal-interacting protein 3 (Dip3), which functions both as an activator to bind DNA in a sequence specific manner and a coactivator to stimulate synergistic activation by Dorsal and Twist [[cite:PUB00018478]].</li> <li>Drosophila Stonewall (Stwl), a putative transcription factor required for maintenance of female germline stem cells as well as oocyte differentiation.</li></ul>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: myb-like protein O-like [Cicer arietinum] gi|502151240|ref|XP_004508343.1| | 9 | ||
| – | Trihelix transcription factor; TAIR: AT2G44730.1 Alcohol dehydrogenase transcription factor Myb/SANT-like family protein; Swiss-Prot: sp|Q9LJG8|ASIL2_ARATH Trihelix transcription factor ASIL2; TrEMBL-Plants: tr|A0A0S3RSF4|A0A0S3RSF4_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0492300 | 7 | ||
| – | Trihelix transcription factor; TAIR: AT2G44730.1 Alcohol dehydrogenase transcription factor Myb/SANT-like family protein; Swiss-Prot: sp|Q9LJG8|ASIL2_ARATH Trihelix transcription factor ASIL2; TrEMBL-Plants: tr|I1KQI5|I1KQI5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0349300 | 10 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 33.33 |