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IPR006808 is a ATP synthase, F0 complex, subunit G, mitochondrial.
<p>This entry represents the G subunit found in the F0 complex of F-ATPases in mitochondria. The function of subunit G is currently unknown. There is no counterpart in chloroplast or bacterial F-ATPases identified so far [[cite:PUB00008578]].</p> <p>Transmembrane ATPases are membrane-bound enzyme complexes/ion transporters that use ATP hydrolysis to drive the transport of protons across a membrane. Some transmembrane ATPases also work in reverse, harnessing the energy from a proton gradient, using the flux of ions across the membrane via the ATPase proton channel to drive the synthesis of ATP.</p> <p>F-ATPases (also known as ATP synthases, F1F0-ATPase, or H(+)-transporting two-sector ATPase) ([ec:7.1.2.2]) are composed of two linked complexes: the F1 ATPase complex is the catalytic core and is composed of 5 subunits (alpha, beta, gamma, delta, epsilon), while the F0 ATPase complex is the membrane-embedded proton channel that is composed of at least 3 subunits (A-C), with additional subunits in mitochondria. Both the F1 and F0 complexes are rotary motors that are coupled back-to-back. In the F1 complex, the central gamma subunit forms the rotor inside the cylinder made of the α(3)β(3) subunits, while in the F0 complex, the ring-shaped C subunits forms the rotor. The two rotors rotate in opposite directions, but the F0 rotor is usually stronger, using the force from the proton gradient to push the F1 rotor in reverse in order to drive ATP synthesis [[cite:PUB00009752]]. These ATPases can also work in reverse in bacteria, hydrolysing ATP to create a proton gradient.</p> <p>The G subunit is a subunit of the F0 complex in mitochondria; its function is not established yet.</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Cellular component | Mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) | All non-F1 subunits of the mitochondrial hydrogen-transporting ATP synthase, including integral and peripheral mitochondrial inner membrane proteins. | ||
| Molecular function | Proton transmembrane transporter activity | Enables the transfer of a proton from one side of a membrane to the other. | ||
| Biological process | ATP synthesis coupled proton transport | The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Mitochondrial ATP synthase subunit G protein [Theobroma cacao] gi|508783270|gb|EOY30526.1| | 4 | ||
| – | Mitochondrial ATP synthase subunit G protein [Theobroma cacao] gi|508783270|gb|EOY30526.1| | 4 | ||
| – | Mitochondrial ATP synthase subunit G protein; TAIR: AT2G19680.1 Mitochondrial ATP synthase subunit G protein; Swiss-Prot: sp|Q28852|ATP5L_BOVIN ATP synthase subunit g, mitochondrial; TrEMBL-Plants: tr|I3S351|I3S351_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0382200 | 4 | ||
| – | Mitochondrial ATP synthase subunit G protein; TAIR: AT2G19680.1 Mitochondrial ATP synthase subunit G protein; Swiss-Prot: sp|Q28852|ATP5L_BOVIN ATP synthase subunit g, mitochondrial; TrEMBL-Plants: tr|I3S351|I3S351_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0382200 | 4 | ||
| – | Mitochondrial ATP synthase g subunit family protein; TAIR: AT2G19680.1 Mitochondrial ATP synthase subunit G protein; Swiss-Prot: sp|P90921|ATPL1_CAEEL Probable ATP synthase subunit g 1, mitochondrial; TrEMBL-Plants: tr|I1M5D9|I1M5D9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0023800 | 5 | ||
| – | Mitochondrial ATP synthase g subunit family protein; TAIR: AT2G19680.1 Mitochondrial ATP synthase subunit G protein; Swiss-Prot: sp|P90921|ATPL1_CAEEL Probable ATP synthase subunit g 1, mitochondrial; TrEMBL-Plants: tr|I1M5D9|I1M5D9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0023800 | 5 | ||
| – | Mitochondrial ATP synthase subunit G protein; TAIR: AT2G19680.1 Mitochondrial ATP synthase subunit G protein; Swiss-Prot: sp|Q9VAW5|LARP_DROME La-related protein 1; TrEMBL-Plants: tr|I3S351|I3S351_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0441700 | 4 | ||
| – | Mitochondrial ATP synthase subunit G protein; TAIR: AT2G19680.1 Mitochondrial ATP synthase subunit G protein; Swiss-Prot: sp|Q9VAW5|LARP_DROME La-related protein 1; TrEMBL-Plants: tr|I3S351|I3S351_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0441700 | 4 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| PTHR12386:SF31 | PANTHER | 1 | 12.50 |