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IPR007130 is a Diacylglycerol acyltransferase.
<p>This family includes diacylglycerol acyltransferases which catalyse the terminal and only committed step in triacylglycerol (TAG) synthesis using diacylglycerol (DAG) and fatty acyl-CoA as substrates. It is required for synthesis and storage of intracellular triglycerides [[cite:PUB00099608], [cite:PUB00055421], [cite:PUB00099607], [cite:PUB00009790], [cite:PUB00010588]]. In yeast, it is involved in lipid particle synthesis from the endoplasmic reticulum, promoting localized TAG production at discrete ER subdomains, and in ergosterol biosynthesis [[cite:PUB00099608], [cite:PUB00055421]].</p> <p>This family also includes Acyl-CoA wax alcohol acyltransferase 1 and 2 (AWAT1/2), which catalyse the formation of ester bonds between fatty alcohols and fatty acyl-CoAs to form wax monoesters [[cite:PUB00099610], [cite:PUB00099609]]. AWAT2 (also known as MFAT) also possesses acyl-CoA retinol acyltransferase (ARAT) activity that catalyses 11-cis-specific retinyl ester synthesis and shows higher catalytic efficiency toward 11-cis-retinol versus 9-cis-retinol, 13-cis-retinol, and all-trans-retinol substrates [[cite:PUB00099611]].</p> <p>Phytyl ester synthase 1/2, chloroplastic, an acyltransferase involved in fatty acid phytyl ester synthesis in chloroplasts, also belongs to this family. This process is required for the maintenance of the photosynthetic membrane integrity during abiotic stress and senescence [[cite:PUB00100302]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Transferase activity, transferring acyl groups other than amino-acyl groups | Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor). |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: diacylglycerol O-acyltransferase 2-like [Cicer arietinum] gi|502153823|ref|XP_004509475.1| | 10 | ||
| – | PREDICTED: acyltransferase-like protein At3g26840, chloroplastic-like [Cicer arietinum] gi|502106585|ref|XP_004492989.1| | 8 | ||
| – | PREDICTED: acyltransferase-like protein At3g26840, chloroplastic-like [Cicer arietinum] gi|502106585|ref|XP_004492989.1| | 11 | ||
| – | PREDICTED: acyltransferase-like protein At1g54570, chloroplastic-like [Cicer arietinum] gi|502113476|ref|XP_004494663.1| | 10 | ||
| – | Diacylglycerol O-acyltransferase [Medicago truncatula] gi|357484297|ref|XP_003612436.1| | 10 | ||
| – | Diacylglycerol O-acyltransferase [Medicago truncatula] gi|357484297|ref|XP_003612436.1| | 8 | ||
| – | Esterase/lipase/thioesterase family protein; TAIR: AT5G41120.3 Esterase/lipase/thioesterase family protein; Swiss-Prot: sp|Q9LW26|Y3684_ARATH Acyltransferase-like protein At3g26840, chloroplastic; TrEMBL-Plants: tr|G7KW54|G7KW54_MEDTR Esterase/lipase/thioesterase family protein; Found in the gene: LotjaGi1g1v0630000 | 17 | ||
| – | Esterase/lipase/thioesterase family protein; TAIR: AT5G41130.1 Esterase/lipase/thioesterase family protein; Swiss-Prot: sp|Q9LW26|Y3684_ARATH Acyltransferase-like protein At3g26840, chloroplastic; TrEMBL-Plants: tr|G7KW54|G7KW54_MEDTR Esterase/lipase/thioesterase family protein; Found in the gene: LotjaGi1g1v0630100 | 17 | ||
| – | Esterase/lipase/thioesterase family protein; TAIR: AT5G41130.1 Esterase/lipase/thioesterase family protein; Swiss-Prot: sp|Q9LW26|Y3684_ARATH Acyltransferase-like protein At3g26840, chloroplastic; TrEMBL-Plants: tr|G7KW54|G7KW54_MEDTR Esterase/lipase/thioesterase family protein; Found in the gene: LotjaGi1g1v0630100 | 17 | ||
| – | Esterase/lipase/thioesterase-like protein; TAIR: AT1G54570.1 Esterase/lipase/thioesterase family protein; Swiss-Prot: sp|Q9ZVN2|Y1457_ARATH Acyltransferase-like protein At1g54570, chloroplastic; TrEMBL-Plants: tr|A0A0R0KP45|A0A0R0KP45_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0777600 | 9 | ||
| – | Esterase/lipase/thioesterase-like protein; TAIR: AT1G54570.1 Esterase/lipase/thioesterase family protein; Swiss-Prot: sp|Q9ZVN2|Y1457_ARATH Acyltransferase-like protein At1g54570, chloroplastic; TrEMBL-Plants: tr|A0A0R0KP45|A0A0R0KP45_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0777600 | 9 | ||
| – | Diacylglycerol O-acyltransferase 2; TAIR: AT3G51520.1 diacylglycerol acyltransferase family; Swiss-Prot: sp|K7K424|DAT2D_SOYBN Diacylglycerol O-acyltransferase 2D; TrEMBL-Plants: tr|G7K2N1|G7K2N1_MEDTR Type 2 acyl-CoA diacylglycerol acyltransferase; Found in the gene: LotjaGi2g1v0351900 | 10 | ||
| – | Diacylglycerol O-acyltransferase 2; TAIR: AT3G51520.1 diacylglycerol acyltransferase family; Swiss-Prot: sp|K7K424|DAT2D_SOYBN Diacylglycerol O-acyltransferase 2D; TrEMBL-Plants: tr|G7K2N1|G7K2N1_MEDTR Type 2 acyl-CoA diacylglycerol acyltransferase; Found in the gene: LotjaGi4g1v0141000 | 10 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 7.69 |