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IPR007379

Source: InterPro

Description

IPR007379 is a Tim44-like domain.

<p>Tim44 is an essential component of the machinery that mediates the translocation of nuclear-encoded proteins across the mitochondrial inner membrane [[cite:PUB00009930]]. Tim44 is thought to bind phospholipids of the mitochondrial inner membrane both by electrostatic interactions and by penetrating the polar head group region [[cite:PUB00009930]]. This entry represents the C-terminal region of Tim44 that has been shown to form a stable proteolytic fragment in yeast. This region is also found in a set of smaller bacterial proteins. The molecular function of the bacterial members is unknown, but transport seems likely. The crystal structure of the C terminus of Tim44 has revealed a large hydrophobic pocket which might play an important role in interacting with the acyl chains of lipid molecules in the mitochondrial membrane [[cite:PUB00040854]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

Unable to find any GO terms for the transcript with the identifier.

Associated Lotus transcripts 2

Transcript Name Description Predicted domains Domain count
Lj5g3v1452200.1
– PREDICTED: probable 39S ribosomal protein L45, mitochondrial-like [Glycine max] gi|356576761|ref|XP_003556498.1|
Domains
7
LotjaGi6g1v0332400.1
– Mitochondrial import inner membrane translocase subunit TIM44; TAIR: AT2G36070.1 translocase inner membrane subunit 44-2; Swiss-Prot: sp|Q5XF06|TI442_ARATH Mitochondrial import inner membrane translocase subunit TIM44-2; TrEMBL-Plants: tr|A0A151SYE9|A0A151SYE9_CAJCA Uncharacterized protein; Found in the gene: LotjaGi6g1v0332400
Domains
9

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 50.00