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IPR007587 is a SIT4 phosphatase-associated protein family.
<p>This entry includes budding yeast Sit4-associated proteins, such as Sap155, Sap185, and Sap190. Sit4 is a phosphatase involved in a variety of processes including transcription, translation, bud formation, glycogen metabolism, monovalent ion homeostasis, H+ transport, and telomere function [[cite:PUB00092454]].</p> <p>This entry also includes mammalian PP6 (Sit4 homologue)-associated proteins, such as PP6R1, PP6R2, and PP6R3 [[cite:PUB00092454]]. They are regulatory subunits of PP6 involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha [[cite:PUB00092454]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Protein phosphatase binding | Interacting selectively and non-covalently with any protein phosphatase. | ||
| Biological process | Regulation of phosphoprotein phosphatase activity | Any process that modulates the frequency, rate or extent of phosphoprotein phosphatase activity, the catalysis of the hydrolysis of phosphate from a phosphoprotein. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: serine/threonine-protein phosphatase 6 regulatory subunit 1-like isoform 1 [Glycine max] gi|356550163|ref|XP_003543458.1| | 4 | ||
| – | PREDICTED: serine/threonine-protein phosphatase 6 regulatory subunit 3-like [Glycine max] gi|356543472|ref|XP_003540184.1| | 4 | ||
| – | PREDICTED: serine/threonine-protein phosphatase 6 regulatory subunit 3-like isoform X1 [Cicer arietinum] gi|502082221|ref|XP_004487101.1| | 4 | ||
| – | PREDICTED: serine/threonine-protein phosphatase 6 regulatory subunit 3-like [Glycine max] gi|356544642|ref|XP_003540757.1| | 5 | ||
| – | PREDICTED: serine/threonine-protein phosphatase 6 regulatory subunit 3-B-like [Cicer arietinum] gi|502145394|ref|XP_004506011.1| | 4 | ||
| – | PREDICTED: serine/threonine-protein phosphatase 6 regulatory subunit 3-like [Glycine max] gi|356532415|ref|XP_003534768.1| | 3 | ||
| – | PREDICTED: serine/threonine-protein phosphatase 6 regulatory subunit 3-like [Glycine max] gi|356532415|ref|XP_003534768.1| | 8 | ||
| – | PREDICTED: serine/threonine-protein phosphatase 6 regulatory subunit 3-like [Glycine max] gi|356543472|ref|XP_003540184.1| | 7 | ||
| – | PREDICTED: serine/threonine-protein phosphatase 6 regulatory subunit 3-like [Glycine max] gi|356543472|ref|XP_003540184.1| | 7 | ||
| – | PREDICTED: serine/threonine-protein phosphatase 6 regulatory subunit 3-like isoform X1 [Cicer arietinum] gi|502082221|ref|XP_004487101.1| | 4 | ||
| – | PREDICTED: serine/threonine-protein phosphatase 6 regulatory subunit 3-like [Glycine max] gi|356544642|ref|XP_003540757.1| | 5 | ||
| – | PREDICTED: serine/threonine-protein phosphatase 6 regulatory subunit 3-like [Glycine max] gi|356532415|ref|XP_003534768.1| | 8 | ||
| – | Serine/threonine-protein phosphatase 6 regulatory subunit 3; TAIR: AT1G30470.2 SIT4 phosphatase-associated family protein; Swiss-Prot: sp|Q5F471|PP6R3_CHICK Serine/threonine-protein phosphatase 6 regulatory subunit 3; TrEMBL-Plants: tr|K7LBE9|K7LBE9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0132600_LC | 6 | ||
| – | Serine/threonine-protein phosphatase 6 regulatory subunit; TAIR: AT1G07990.1 SIT4 phosphatase-associated family protein; Swiss-Prot: sp|Q5F471|PP6R3_CHICK Serine/threonine-protein phosphatase 6 regulatory subunit 3; TrEMBL-Plants: tr|A0A0B2P8K2|A0A0B2P8K2_GLYSO Serine/threonine-protein phosphatase 6 regulatory subunit 3; Found in the gene: LotjaGi2g1v0359000 | 5 | ||
| – | Serine/threonine-protein phosphatase 6 regulatory subunit; TAIR: AT1G07990.1 SIT4 phosphatase-associated family protein; Swiss-Prot: sp|Q5H9R7|PP6R3_HUMAN Serine/threonine-protein phosphatase 6 regulatory subunit 3; TrEMBL-Plants: tr|A0A0B2P8K2|A0A0B2P8K2_GLYSO Serine/threonine-protein phosphatase 6 regulatory subunit 3; Found in the gene: LotjaGi2g1v0359000 | 5 | ||
| – | Serine/threonine-protein phosphatase 6 regulatory subunit; TAIR: AT1G07990.1 SIT4 phosphatase-associated family protein; Swiss-Prot: sp|Q5F471|PP6R3_CHICK Serine/threonine-protein phosphatase 6 regulatory subunit 3; TrEMBL-Plants: tr|I1LTJ8|I1LTJ8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0163500 | 5 | ||
| – | Serine/threonine-protein phosphatase 6 regulatory subunit; TAIR: AT1G07990.1 SIT4 phosphatase-associated family protein; Swiss-Prot: sp|Q5F471|PP6R3_CHICK Serine/threonine-protein phosphatase 6 regulatory subunit 3; TrEMBL-Plants: tr|I1LTJ8|I1LTJ8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0163500 | 5 | ||
| – | Serine/threonine-protein phosphatase 6 regulatory subunit; TAIR: AT1G07990.1 SIT4 phosphatase-associated family protein; Swiss-Prot: sp|Q9UPN7|PP6R1_HUMAN Serine/threonine-protein phosphatase 6 regulatory subunit 1; TrEMBL-Plants: tr|I1LTJ8|I1LTJ8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0163500 | 7 | ||
| – | Serine/threonine-protein phosphatase 6 regulatory subunit; TAIR: AT1G07990.1 SIT4 phosphatase-associated family protein; Swiss-Prot: sp|Q9UPN7|PP6R1_HUMAN Serine/threonine-protein phosphatase 6 regulatory subunit 1; TrEMBL-Plants: tr|I1LTJ8|I1LTJ8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0163500 | 7 | ||
| – | Serine/threonine-protein phosphatase 6 regulatory subunit 3; TAIR: AT1G30470.1 SIT4 phosphatase-associated family protein; Swiss-Prot: sp|Q5H9R7|PP6R3_HUMAN Serine/threonine-protein phosphatase 6 regulatory subunit 3; TrEMBL-Plants: tr|K7LBE9|K7LBE9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0272300 | 7 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 5.00 |