Domain Predictions — View

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IPR007788

Source: InterPro

Description

IPR007788 is a Glutaminyl-peptide cyclotransferase.

<p>QCT converts glutamine and N-terminal glutamyl residues in peptides to 5-oxoproline and 5-oxoproline residues [[cite:PUB00053847], [cite:PUB00053848]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on April 27, 2020, while the GO metadata was last updated on April 27, 2020.

GO term	Namespace	Name	Definition	Relationships
GO:0016603 View details of GO:0016603 AmiGO InterPro QuickGO	Molecular function	Glutaminyl-peptide cyclotransferase activity	Catalysis of the reaction: L-glutaminyl-peptide = 5-oxoprolyl-peptide + NH3.	Subterm of GO:0016755
GO:0017186 View details of GO:0017186 AmiGO InterPro QuickGO	Biological process	Peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase	The chemical reactions and pathways resulting in the formation of peptidyl-pyroglutamic acid, catalyzed by glutaminyl-peptide cyclotransferase.	Subterm of GO:0018199

Associated Lotus transcripts 2

Transcript	Name	Description	Predicted domains	Domain count
Lj0g3v0208589.1 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	PREDICTED: glutaminyl-peptide cyclotransferase-like [Cicer arietinum] gi\|502181740\|ref\|XP_004516875.1\|	Domains G3DSA:2.130.10.10 IPR007788 IPR015943 NON_CYTOPLASMIC_DOMAIN PF05096 PTHR31270 PTHR31270:SF0 SIGNAL_PEPTIDE SIGNAL_PEPTIDE_C_REGION SIGNAL_PEPTIDE_H_REGION SIGNAL_PEPTIDE_N_REGION SSF63825 TMhelix mobidb-lite	14
LotjaGi2g1v0124200.1 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	Glutaminyl-peptide cyclotransferase; TAIR: AT4G25720.1 glutaminyl cyclase; Swiss-Prot: sp\|Q84WV9\|QPCT_ARATH Glutaminyl-peptide cyclotransferase; TrEMBL-Plants: tr\|I3S2G5\|I3S2G5_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0124200	Domains CYTOPLASMIC_DOMAIN IPR007788 IPR011044 NON_CYTOPLASMIC_DOMAIN PF05096 PTHR31270 PTHR31270:SF1 SSF50969 TMhelix TRANSMEMBRANE mobidb-lite	11

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain	Source	Observations	Saturation (%)
mobidb-lite	MobiDBLite	1	50.00