Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message

IPR007918

Description

IPR007918 is a Mitochondrial distribution/morphology family 35/apoptosis.

<p>This is a family of small highly conserved proteins. In Saccharomyces cerevisiae (Baker's yeast) the gene YKL053C-A (MDM35) [swissprot:O60200] is one of the genes essential for maintenance of normal mitochondrial distribution and morphology (MDM) [[cite:PUB00033261]]; wherease in Homo sapiens (Human), p53CSV, [swissprot:O43715] is a direct transcriptional target for p53 and appears to be a cell-survival mediator in response to genotoxic stress including low-levels of DNA damage. It is suggested that p53CSV modulates the apoptotic pathway through interaction with HSP70 and Apaf-1 thereby inhibiting activation of procaspase-3 and procaspase-9 [[cite:PUB00033262]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

Unable to find any GO terms for the transcript with the identifier.

Associated Lotus transcripts 1

Transcript Name Description Predicted domains Domain count
Uncharacterized protein TCM_037337 [Theobroma cacao] gi|508782725|gb|EOY29981.1| 3

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
PTHR21329 PANTHER 1 100.00