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IPR008698

Source: InterPro

Description

IPR008698 is a NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7, NDUB7.

<p>NADH:ubiquinone oxidoreductase (complex I) ([ec:7.1.1.2]) is a respiratory-chain enzyme that catalyses the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane (NADH + ubiquinone = NAD+ + ubiquinol) [[cite:PUB00005074]]. Complex I is a major source of reactive oxygen species (ROS) that are predominantly formed by electron transfer from FMNH(2). Complex I is found in bacteria, cyanobacteria (as a NADH-plastoquinone oxidoreductase), archaea [[cite:PUB00043561]], mitochondria, and in the hydrogenosome, a mitochondria-derived organelle. In general, the bacterial complex consists of 14 different subunits, while the mitochondrial complex contains homologues to these subunits in addition to approximately 31 additional proteins [[cite:PUB00045437]].</p> <p>This family consists of the accessory subunit of complex I NADH-ubiquinone oxidoreductase NDUB7 (or NDUFB7, also known as B18), which is not involved in catalysis [[cite:PUB00086570], [cite:PUB00097152]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0003954
Molecular function NADH dehydrogenase activity Catalysis of the reaction: NADH + H+ + acceptor = NAD+ + reduced acceptor.
Subterm of
GO:0005739
Cellular component Mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
Subterm of
GO:0008137
Molecular function NADH dehydrogenase (ubiquinone) activity Catalysis of the reaction: NADH + H+ + ubiquinone = NAD+ + ubiquinol.
Subterm of

Associated Lotus transcripts 1

Transcript Name Description Predicted domains Domain count
LotjaGi5g1v0347500.1
– NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7; TAIR: AT2G02050.1 NADH-ubiquinone oxidoreductase B18 subunit; Swiss-Prot: sp|Q9SKC9|NDUB7_ARATH NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7; TrEMBL-Plants: tr|A0A072VQV0|A0A072VQV0_MEDTR NADH-ubiquinone oxidoreductase B18 subunit, putative; Found in the gene: LotjaGi5g1v0347500
Domains
5

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 100.00