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IPR009448

Description

IPR009448 is a UDP-glucose:Glycoprotein Glucosyltransferase.

<p>The N-terminal region of this group of proteins is required for correct folding of the ER UDP-Glc: glucosyltransferase. These proteins selectively reglucosylates unfolded glycoproteins, thus providing quality control for protein transport out of the ER. Unfolded, denatured glycoproteins are substantially better substrates for glucosylation by this enzyme than are the corresponding native proteins. This protein and transient glucosylation may be involved in monitoring and/or assisting the folding and assembly of newly made glycoproteins, in order to identify glycoproteins that need assistance in folding from chaperones</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
Molecular function UDP-glucose:glycoprotein glucosyltransferase activity Catalysis of the addition of UDP-glucose on to asparagine-linked (N-linked) oligosaccharides of the form Man7-9GlcNAc2 on incorrectly folded glycoproteins.
Biological process Protein glycosylation A protein modification process that results in the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.

Associated Lotus transcripts 11

Transcript Name Description Predicted domains Domain count
PREDICTED: LOW QUALITY PROTEIN: UDP-glucose:glycoprotein glucosyltransferase-like [Cicer arietinum] gi|502076910|ref|XP_004485494.1| 19
PREDICTED: UDP-glucose:glycoprotein glucosyltransferase-like [Glycine max] gi|356528807|ref|XP_003532989.1| 11
PREDICTED: LOW QUALITY PROTEIN: UDP-glucose:glycoprotein glucosyltransferase-like [Cicer arietinum] gi|502076910|ref|XP_004485494.1| 16
UDP-glucose:glycoprotein glucosyltransferase; TAIR: AT1G71220.1 EMS-MUTAGENIZED BRI1 SUPPRESSOR 1; Swiss-Prot: sp|Q0WL80|UGGG_ARATH UDP-glucose:glycoprotein glucosyltransferase; TrEMBL-Plants: tr|A0A0L9VGE3|A0A0L9VGE3_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0358100_LC 12
UDP-glucose:glycoprotein glucosyltransferase; TAIR: AT1G71220.2 EMS-MUTAGENIZED BRI1 SUPPRESSOR 1; Swiss-Prot: sp|Q0WL80|UGGG_ARATH UDP-glucose:glycoprotein glucosyltransferase; TrEMBL-Plants: tr|A0A0L9VGE3|A0A0L9VGE3_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0358100_LC 12
UDP-glucose:glycoprotein glucosyltransferase; TAIR: AT1G71220.1 EMS-MUTAGENIZED BRI1 SUPPRESSOR 1; Swiss-Prot: sp|Q0WL80|UGGG_ARATH UDP-glucose:glycoprotein glucosyltransferase; TrEMBL-Plants: tr|A0A0L9VGE3|A0A0L9VGE3_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0358100_LC 12
UDP-glucose:glycoprotein glucosyltransferase; TAIR: AT1G71220.2 EMS-MUTAGENIZED BRI1 SUPPRESSOR 1; Swiss-Prot: sp|Q0WL80|UGGG_ARATH UDP-glucose:glycoprotein glucosyltransferase; TrEMBL-Plants: tr|A0A0L9VGE3|A0A0L9VGE3_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0358100_LC 12
UDP-glucose:glycoprotein glucosyltransferase; TAIR: AT1G71220.2 EMS-MUTAGENIZED BRI1 SUPPRESSOR 1; Swiss-Prot: sp|Q0WL80|UGGG_ARATH UDP-glucose:glycoprotein glucosyltransferase; TrEMBL-Plants: tr|A0A0L9VGE3|A0A0L9VGE3_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0358100_LC 12
UDP-glucose:glycoprotein glucosyltransferase; TAIR: AT1G71220.1 EMS-MUTAGENIZED BRI1 SUPPRESSOR 1; Swiss-Prot: sp|Q0WL80|UGGG_ARATH UDP-glucose:glycoprotein glucosyltransferase; TrEMBL-Plants: tr|I3T6G1|I3T6G1_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0360400_LC 10
UDP-glucose:glycoprotein glucosyltransferase; TAIR: AT1G71220.1 EMS-MUTAGENIZED BRI1 SUPPRESSOR 1; Swiss-Prot: sp|Q0WL80|UGGG_ARATH UDP-glucose:glycoprotein glucosyltransferase; TrEMBL-Plants: tr|I1KUN0|I1KUN0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0360500 27
UDP-glucose:glycoprotein glucosyltransferase; TAIR: AT1G71220.1 EMS-MUTAGENIZED BRI1 SUPPRESSOR 1; Swiss-Prot: sp|Q0WL80|UGGG_ARATH UDP-glucose:glycoprotein glucosyltransferase; TrEMBL-Plants: tr|I1KUN0|I1KUN0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0360500 17

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 9.09