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IPR011893

Source: InterPro

Description

IPR011893 is a Selenoprotein, Rdx-type.

<p>This entry represents the Rdx family of selenoproteins, which includes mammalian selenoproteins SelW, SelV, SelT and SelH, bacterial SelW-like proteins and cysteine-containing proteins of unknown function in all three domains of life. Mammalian Rdx12 and its fish selenoprotein orthologues are also members of this family [[cite:PUB00053376]]. These proteins possess a thioredoxin-like fold and a conserved CXXC or CxxU (U is selenocysteine) motif near the N terminus, suggesting a redox function. Rdx proteins can use catalytic cysteine (or selenocysteine) to form transient mixed disulphides with substrate proteins. Selenium (Se) plays an essential role in cell survival and most of the effects of Se are probably mediated by selenoproteins.</p> <p>Selenoprotein W (SelW) plays an important role in protection of neurons from oxidative stress during neuronal development [[cite:PUB00053377], [cite:PUB00010227]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

Unable to find any GO terms for the transcript with the identifier.

Associated Lotus transcripts 3

Transcript Name Description Predicted domains Domain count
Lj2g3v2279590.1
– SelT-like protein [Medicago truncatula] gi|357490829|ref|XP_003615702.1|
Domains
15
LotjaGi1g1v0119100.1
– SelT-like protein; TAIR: AT3G47300.1 SELT-like protein precursor; Swiss-Prot: sp|Q9STZ2|SELT_ARATH SelT-like protein; TrEMBL-Plants: tr|I3SFL1|I3SFL1_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0119100
Domains
15
LotjaGi3g1v0194000.1
– SelT-like protein; TAIR: AT3G47300.1 SELT-like protein precursor; Swiss-Prot: sp|Q9STZ2|SELT_ARATH SelT-like protein; TrEMBL-Plants: tr|I3TAK2|I3TAK2_LOTJA Uncharacterized protein; Found in the gene: LotjaGi3g1v0194000
Domains
17

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 33.33