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IPR013930 is a RPAP1, N-terminal.
<p>This entry represents the N-terminal region of RPAP-1 that is conserved from yeast to humans.</p> <p>In Saccharomyces cerevisiae (Bakers yeast), inhibition of RNA polymerase II-associated protein 1 (RPAP1) synthesis leads to global changes in gene expression that closely resemble those observed upon loss of the RNAPII subunit Rpb11 [[cite:PUB00033321]]. RPAP1 forms an interface between the RNA polymerase II enzyme and chaperone or scaffolding proteins, suggesting its essential role in linking RNA polymerase II to regulators involved in protein complex formation. Furthermore, it is required for the interaction of the RNA polymerase II complex with acetylated histone H3, indicating a function in the coordination between transcription and chromatin modification.</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | RNA polymerase II-associated protein [Medicago truncatula] gi|357487829|ref|XP_003614202.1| | 5 | ||
| – | RNA polymerase II-associated protein 1; TAIR: AT4G38440.1 RPAP1-like, carboxy-terminal protein; Swiss-Prot: sp|Q8GYU3|IYO_ARATH Transcriptional elongation regulator MINIYO; TrEMBL-Plants: tr|A0A0R0LFZ5|A0A0R0LFZ5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0291900 | 8 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 50.00 |