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IPR016274 is a Histidine acid phosphatase, eukaryotic.
<p>This family represents eukaryotic histidine acid phosphatases, including Phytase A from Aspergillus oryzae (PhyA) and human Multiple inositol polyphosphate phosphatase 1 (MINPP1). PhyA catalyses the phosphate monoester hydrolysis of phytic acid (myo-inositol hexakisphosphate) with the subsequent formation of myo-inositol pentakis-, tetrakis-, tris-, bis-, and monophosphates, as well as the liberation of inorganic phosphate [[cite:PUB00153142]]. MINPP1 regulates intracellular inositol polyphosphates pools, which act as metal chelators, it may control the availability of intracellular calcium and iron, which are important for proper neuronal development and homeostasis [[cite:PUB00153140] , [cite:PUB00153141]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Phosphatase activity | Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Multiple inositol polyphosphate phosphatase 1; TAIR: AT1G09870.1 histidine acid phosphatase family protein; Swiss-Prot: sp|Q54ND5|MINP1_DICDI Multiple inositol polyphosphate phosphatase 1; TrEMBL-Plants: tr|K7MPH5|K7MPH5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0079100 | 18 | ||
| – | Multiple inositol polyphosphate phosphatase 1; TAIR: AT1G09870.1 histidine acid phosphatase family protein; Swiss-Prot: sp|Q54ND5|MINP1_DICDI Multiple inositol polyphosphate phosphatase 1; TrEMBL-Plants: tr|K7MPH5|K7MPH5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0079100 | 18 | ||
| – | Multiple inositol polyphosphate phosphatase 1; TAIR: AT1G09870.1 histidine acid phosphatase family protein; Swiss-Prot: sp|Q54ND5|MINP1_DICDI Multiple inositol polyphosphate phosphatase 1; TrEMBL-Plants: tr|K7MPH5|K7MPH5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0079100 | 18 | ||
| – | Multiple inositol polyphosphate phosphatase 1; TAIR: AT1G09870.1 histidine acid phosphatase family protein; Swiss-Prot: sp|Q54ND5|MINP1_DICDI Multiple inositol polyphosphate phosphatase 1; TrEMBL-Plants: tr|K7MPH5|K7MPH5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0079100 | 18 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd07061 | CDD | 1 | 25.00 |