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IPR016657 is a Phosphoacetylglucosamine mutase.
<p>This group represents a phosphoacetylglucosamine mutase (PAGM; also known as phosphoglucomutase 3 or N-acetylglucosamine-phosphate mutase [[cite:PUB00080841]]). It is an essential enzyme found in eukaryotes that reversibly catalyzes the conversion of GlcNAc-6-phosphate into GlcNAc-1-phosphate as part of the UDP-N-acetylglucosamine (UDP-GlcNAc) biosynthetic pathway. UDP-GlcNAc is an essential metabolite that serves as the biosynthetic precursor of many glycoproteins and mucopolysaccharides. PAGM is a member of the alpha-D-phosphohexomutase superfamily [[cite:PUB00040263]], which catalyzes the intramolecular phosphoryl transfer of sugar substrates [[cite:PUB00080845]]. The alpha-D-phosphohexomutases have four domains with a centrally located active site formed by four loops, one from each domain [[cite:PUB00042563]]. All four domains are included in this alignment model.</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Phosphoacetylglucosamine mutase activity | Catalysis of the reaction: N-acetyl-alpha-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine 6-phosphate. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: phosphoacetylglucosamine mutase-like [Cicer arietinum] gi|502160492|ref|XP_004511763.1| | 16 | ||
| – | Phosphoglucosamine mutase; TAIR: AT5G18070.1 phosphoglucosamine mutase-like protein; Swiss-Prot: sp|P57750|AGM1_ARATH Phosphoacetylglucosamine mutase; TrEMBL-Plants: tr|G7JZT7|G7JZT7_MEDTR Phosphogluco-mutase; Found in the gene: LotjaGi2g1v0416600 | 17 | ||
| – | Phosphoglucosamine mutase; TAIR: AT5G18070.1 phosphoglucosamine mutase-like protein; Swiss-Prot: sp|P57750|AGM1_ARATH Phosphoacetylglucosamine mutase; TrEMBL-Plants: tr|G7JZT7|G7JZT7_MEDTR Phosphogluco-mutase; Found in the gene: LotjaGi2g1v0416600 | 17 | ||
| – | Phosphoglucosamine mutase; TAIR: AT5G18070.1 phosphoglucosamine mutase-like protein; Swiss-Prot: sp|P57750|AGM1_ARATH Phosphoacetylglucosamine mutase; TrEMBL-Plants: tr|G7JZT7|G7JZT7_MEDTR Phosphogluco-mutase; Found in the gene: LotjaGi2g1v0416600 | 17 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd03086 | CDD | 1 | 25.00 |