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IPR018491 is a SLC12A transporter, C-terminal.
<p>This entry represents a domain found in the C-terminal of the solute carrier family 12 (SLC12) members, which are K-Cl cotransporters. The SLC12 family members are predicted to have 12 transmembrane (TM) regions in a central hydrophobic domain, together with hydrophilic N- and C-termini that are likely cytoplasmic. Comparison of their sequences with those of other ion-tranporting membrane proteins reveals that they are part of a new superfamily of cation-chloride co-transporters, which includes the Na-Cl and Na-K-2Cl co-transporters [[cite:PUB00002956], [cite:PUB00004291], [cite:PUB00044874]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Biological process | Ion transport | The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. | ||
| Cellular component | Membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. | ||
| Molecular function | Transmembrane transporter activity | Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Cation-chloride cotransporter-like protein [Lotus tenuis] gi|190411131|gb|ACE78321.1| | 13 | ||
| – | Cation-chloride cotransporter 1; TAIR: AT1G30450.1 cation-chloride co-transporter 1; Swiss-Prot: sp|Q2UVJ5|CCC1_ARATH Cation-chloride cotransporter 1; TrEMBL-Plants: tr|B3VBE9|B3VBE9_9FABA Cation-chloride cotransporter-like protein; Found in the gene: LotjaGi6g1v0212700 | 14 | ||
| – | Cation-chloride cotransporter 1; TAIR: AT1G30450.4 cation-chloride co-transporter 1; Swiss-Prot: sp|Q6Z0E2|CCC1_ORYSJ Cation-chloride cotransporter 1; TrEMBL-Plants: tr|B3VBE9|B3VBE9_9FABA Cation-chloride cotransporter-like protein; Found in the gene: LotjaGi6g1v0212700 | 16 | ||
| – | Cation-chloride cotransporter 1; TAIR: AT1G30450.1 cation-chloride co-transporter 1; Swiss-Prot: sp|Q2UVJ5|CCC1_ARATH Cation-chloride cotransporter 1; TrEMBL-Plants: tr|B3VBE9|B3VBE9_9FABA Cation-chloride cotransporter-like protein; Found in the gene: LotjaGi6g1v0212700 | 13 | ||
| – | Cation-chloride cotransporter 1; TAIR: AT1G30450.1 cation-chloride co-transporter 1; Swiss-Prot: sp|Q2UVJ5|CCC1_ARATH Cation-chloride cotransporter 1; TrEMBL-Plants: tr|B3VBE9|B3VBE9_9FABA Cation-chloride cotransporter-like protein; Found in the gene: LotjaGi6g1v0212700 | 13 | ||
| – | Cation-chloride cotransporter 1; TAIR: AT1G30450.1 cation-chloride co-transporter 1; Swiss-Prot: sp|Q2UVJ5|CCC1_ARATH Cation-chloride cotransporter 1; TrEMBL-Plants: tr|B3VBE9|B3VBE9_9FABA Cation-chloride cotransporter-like protein; Found in the gene: LotjaGi6g1v0212700 | 14 | ||
| – | Cation-chloride cotransporter 1; TAIR: AT1G30450.4 cation-chloride co-transporter 1; Swiss-Prot: sp|Q6Z0E2|CCC1_ORYSJ Cation-chloride cotransporter 1; TrEMBL-Plants: tr|B3VBE9|B3VBE9_9FABA Cation-chloride cotransporter-like protein; Found in the gene: LotjaGi6g1v0212700 | 16 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| TRANSMEMBRANE | Phobius | 1 | 14.29 |