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IPR019008

Source: InterPro

Description

IPR019008 is a ER membrane protein complex subunit 7, beta-sandwich domain.

<p>This is the β-sandwich domain found in ER membrane protein complex subunit 7 (EMC7) [[cite:PUB00096682], [cite:PUB00096681]], which is an integral membrane component of the EMC. EMC is widely conserved and involved in membrane protein biogenesis. It mediates the insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins in an energy-independent manner, both post-translational insertion of tail-anchored proteins and co-translational insertion of multipass membrane proteins [[cite:PUB00096679], [cite:PUB00096678]]. This entry includes UPF0620 protein C83.10 from S. pombe, an orthologue from animal EMC7.</p> <p>This domain is also found in nodal modulators, which have been identified as part of a protein complex that participates in the nodal signalling pathway during vertebrate development [[cite:PUB00054165]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

Unable to find any GO terms for the transcript with the identifier.

Associated Lotus transcripts 2

Transcript Name Description Predicted domains Domain count
Lj1g3v1856390.1
– PREDICTED: UPF0480 protein At4g32130-like [Glycine max] gi|356507608|ref|XP_003522556.1|
Domains
19
LotjaGi1g1v0381600.1
– Er membrane protein complex subunit 7-like protein; TAIR: AT2G25310.1 ER membrane protein complex subunit-like protein (DUF2012); Swiss-Prot: sp|Q8VY97|Y4213_ARATH ER membrane protein complex subunit 7 homolog; TrEMBL-Plants: tr|I3S1N4|I3S1N4_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0381600
Domains
19

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 50.00