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IPR019800 is a Glycoside hydrolase, family 3, active site.
<p>O-Glycosyl hydrolases ([ec:3.2.1.]) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families [[cite:PUB00004870], [cite:PUB00005266]]. This classification is available on the CAZy (CArbohydrate-Active EnZymes) website.</p> <p>Glycoside hydrolase family 3 [cazy:GH3] comprises enzymes with a number of known activities; beta-glucosidase ([ec:3.2.1.21]); beta-xylosidase ([ec:3.2.1.37]); N-acetyl beta-glucosaminidase ([ec:3.2.1.52]); glucan beta-1,3-glucosidase ([ec:3.2.1.58]); cellodextrinase ([ec:3.2.1.74]); exo-1,3-1,4-glucanase ([ec:3.2.1]). These enzymes are two-domain globular proteins that are N-glycosylated at three sites [[cite:PUB00005846]]. This domain is often N-terminal to the glycoside hydrolase family 3, C-terminal domain [interpro:IPR002772].<p>The signature pattern in these enzymes is centred on a conserved aspartic acid residue which has been shown [[cite:PUB00000578]], in Aspergillus wentii beta-glucosidase A3, to be implicated in the catalytic mechanism.</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Hydrolase activity, hydrolyzing O-glycosyl compounds | Catalysis of the hydrolysis of any O-glycosyl bond. | ||
| Biological process | Carbohydrate metabolic process | The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: lysosomal beta glucosidase-like [Cicer arietinum] gi|502129232|ref|XP_004500232.1| | 15 | ||
| – | Beta-glucosidase; TAIR: AT3G47000.1 Glycosyl hydrolase family protein; Swiss-Prot: sp|A7LXU3|BGH3B_BACO1 Beta-glucosidase BoGH3B; TrEMBL-Plants: tr|I1JHB3|I1JHB3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0123200 | 11 | ||
| – | Beta-glucosidase; TAIR: AT3G47000.1 Glycosyl hydrolase family protein; Swiss-Prot: sp|A7LXU3|BGH3B_BACO1 Beta-glucosidase BoGH3B; TrEMBL-Plants: tr|A0A151RS31|A0A151RS31_CAJCA Lysosomal beta glucosidase; Found in the gene: LotjaGi1g1v0123200 | 16 | ||
| – | Beta-glucosidase; TAIR: AT3G47000.1 Glycosyl hydrolase family protein; Swiss-Prot: sp|A7LXU3|BGH3B_BACO1 Beta-glucosidase BoGH3B; TrEMBL-Plants: tr|A0A072UWG8|A0A072UWG8_MEDTR Glycoside hydrolase family 3 protein; Found in the gene: LotjaGi6g1v0132600 | 16 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| SSF52279 | SUPERFAMILY | 1 | 25.00 |