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IPR021622 is a Afadin/alpha-actinin-binding.
<p>This family is found in mammals where it is localised at cell-cell adherens junctions [[cite:PUB00053518]], and in Sch. pombe and other fungi where it anchors spindle-pole bodies to spindle microtubules [[cite:PUB00053519]]. It is a coiled-coil structure, and in pombe, it is required for anchoring the minus end of spindle microtubules to the centrosome equivalent, the spindle-pole body. The name ADIP derives from the family being composed of Afadin- and alpha Actinin-Binding Proteins Localised at Cell-Cell Adherens Junctions.</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: interaptin-like isoform X2 [Cicer arietinum] gi|502150246|ref|XP_004507860.1| | 5 | ||
| – | PREDICTED: interaptin-like isoform X1 [Cicer arietinum] gi|502150244|ref|XP_004507859.1| | 4 | ||
| – | Afadin-and alpha-actinin-binding protein; TAIR: AT5G57410.1 Afadin/alpha-actinin-binding protein; Swiss-Prot: sp|Q8CGZ2|ADIP_RAT Afadin- and alpha-actinin-binding protein; TrEMBL-Plants: tr|A0A151SRU4|A0A151SRU4_CAJCA Afadin-and alpha-actinin-binding protein; Found in the gene: LotjaGi4g1v0301600 | 5 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| PTHR47057:SF2 | PANTHER | 1 | 33.33 |