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IPR026019 is a Ribulose-phosphate 3-epimerase.
<p>Ribulose-phosphate 3-epimerase ([ec:5.1.3.1]) (also known as RPE, pentose-5-phosphate 3-epimerase or PPE) is the enzyme that converts D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate in Calvin's reductive pentose phosphate cycle. In Ralstonia eutropha (Alcaligenes eutrophus) two copies of the gene coding for PPE are known [[cite:PUB00002204]], one is chromosomally encoded [swissprot:P40117], the other one is on a plasmid [swissprot:Q04539]. PPE has been found in a wide range of bacteria, archaebacteria, fungi and plants. All the proteins have from 209 to 241 amino acid residues. The enzyme has a TIM barrel structure.</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Ribulose-phosphate 3-epimerase activity | Catalysis of the reaction: D-ribulose 5-phosphate = D-xylulose 5-phosphate. | ||
| Biological process | Pentose-phosphate shunt | The glucose-6-phosphate catabolic process in which, coupled to NADPH synthesis, glucose-6-P is oxidized with the formation of carbon dioxide (CO2) and ribulose 5-phosphate; ribulose 5-P then enters a series of reactions interconverting sugar phosphates. The pentose phosphate pathway is a major source of reducing equivalents for biosynthesis reactions and is also important for the conversion of hexoses to pentoses. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Ribulose-phosphate 3-epimerase; TAIR: AT3G01850.1 Aldolase-type TIM barrel family protein; Swiss-Prot: sp|Q9SE42|RPE1_ORYSJ Ribulose-phosphate 3-epimerase, cytoplasmic isoform; TrEMBL-Plants: tr|I3S751|I3S751_LOTJA Ribulose-phosphate 3-epimerase; Found in the gene: LotjaGi1g1v0622400 | 15 | ||
| – | Ribulose-phosphate 3-epimerase; TAIR: AT5G61410.1 D-ribulose-5-phosphate-3-epimerase; Swiss-Prot: sp|Q43157|RPE_SPIOL Ribulose-phosphate 3-epimerase, chloroplastic; TrEMBL-Plants: tr|I3S6Q9|I3S6Q9_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0250500 | 14 | ||
| – | Ribulose-phosphate 3-epimerase; TAIR: AT5G61410.1 D-ribulose-5-phosphate-3-epimerase; Swiss-Prot: sp|Q43157|RPE_SPIOL Ribulose-phosphate 3-epimerase, chloroplastic; TrEMBL-Plants: tr|I3S6Q9|I3S6Q9_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0250500 | 15 | ||
| – | Ribulose-phosphate 3-epimerase; TAIR: AT5G61410.1 D-ribulose-5-phosphate-3-epimerase; Swiss-Prot: sp|Q43157|RPE_SPIOL Ribulose-phosphate 3-epimerase, chloroplastic; TrEMBL-Plants: tr|I3S6Q9|I3S6Q9_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0250500 | 21 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd00429 | CDD | 1 | 25.00 |