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IPR026058 is a LIPIN family.
<p>Lipin family consists of lipin proteins, which are magnesium-dependent phosphatidate phosphatase enzymes that provide diacylglycerol for synthesis of triacylglycerol and phospholipids. Mammalian lipin proteins also exhibit transcriptional coactivator activity [[cite:PUB00059931]].</p> <p>Common polymorphisms in human LPIN1 and LPIN2 genes are associated with traits underlying common metabolic diseases, including increased adiposity, hypertension, insulin sensitivity, and response to commonly used antidiabetic drugs [[cite:PUB00059931]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Phosphatidate phosphatase, Lipin; TAIR: AT5G42870.1 phosphatidic acid phosphohydrolase 2; Swiss-Prot: sp|Q9FMN2|PAH2_ARATH Phosphatidate phosphatase PAH2; TrEMBL-Plants: tr|K7KHY1|K7KHY1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0354400 | 12 | ||
| – | Phosphatidate phosphatase, Lipin; TAIR: AT3G09560.1 Lipin family protein; Swiss-Prot: sp|Q9SF47|PAH1_ARATH Phosphatidate phosphatase PAH1; TrEMBL-Plants: tr|K7MYX1|K7MYX1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0696400 | 14 | ||
| – | Phosphatidate phosphatase, Lipin; TAIR: AT5G42870.1 phosphatidic acid phosphohydrolase 2; Swiss-Prot: sp|Q9FMN2|PAH2_ARATH Phosphatidate phosphatase PAH2; TrEMBL-Plants: tr|I1MXP5|I1MXP5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0028700 | 12 | ||
| – | Phosphatidate phosphatase, Lipin; TAIR: AT3G09560.1 Lipin family protein; Swiss-Prot: sp|Q9SF47|PAH1_ARATH Phosphatidate phosphatase PAH1; TrEMBL-Plants: tr|I1LYX3|I1LYX3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0071200 | 14 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 25.00 |