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IPR026907

Description

IPR026907 is a Cyclin-D1-binding protein 1-like.

<p>Cyclin-D1-binding protein 1 (CCNDBP1, also known as GCIP) is a helix-loop-helix protein that may negatively regulate cell cycle progression and could function in tumour suppression [[cite:PUB00062257]]. It may act, at least in part, via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription [[cite:PUB00061998], [cite:PUB00062036]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
Biological process Regulation of cell cycle Any process that modulates the rate or extent of progression through the cell cycle.

Associated Lotus transcripts 4

Transcript Name Description Predicted domains Domain count
PREDICTED: cyclin-D1-binding protein 1 homolog [Cicer arietinum] gi|502120577|ref|XP_004497009.1| 5
PREDICTED: cyclin-D1-binding protein 1 homolog [Cicer arietinum] gi|502120577|ref|XP_004497009.1| 5
4
Cyclin-D1-binding protein 1 like; TAIR: AT1G22970.1 cyclin-D1-binding protein; Swiss-Prot: sp|Q5U4I3|CCDB1_XENLA Cyclin-D1-binding protein 1 homolog; TrEMBL-Plants: tr|A0A0B2SDP6|A0A0B2SDP6_GLYSO Cyclin-D1-binding protein 1 like; Found in the gene: LotjaGi5g1v0333100 5

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 25.00