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IPR030482

Source: InterPro

Description

IPR030482 is a p53 and DNA damage-regulated protein 1.

<p>p53 and DNA damage-regulated protein 1 (PDRG) mRNA is upregulated by ultraviolet radiation (UV) but downregulated by tumour suppressor p53 [[cite:PUB00072995]]. Its expression is increased in multiple human malignancies, suggesting that it could play a role in cancer development and/or progression [[cite:PUB00073741]]. It belongs to the prefoldin subunit beta family, whose members are chaperone complex subunits. The function of PDRG is not clear.</p>

This description is obtained from EB-eye REST.

Associated GO terms

Unable to find any GO terms for the transcript with the identifier.

Associated Lotus transcripts 4

Transcript Name Description Predicted domains Domain count
Lj3g3v0509630.1
– P53 and DNA damage-regulated protein 1 [Theobroma cacao] gi|508704469|gb|EOX96365.1|
Domains
3
LotjaGi3g1v0063100.1
– P53/DNA damage-regulated protein; TAIR: AT3G15351.1 P53/DNA damage-regulated protein; Swiss-Prot: sp|Q642A0|PDRG1_RAT p53 and DNA damage-regulated protein 1; TrEMBL-Plants: tr|K7L1B3|K7L1B3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0063100
Domains
2
LotjaGi3g1v0063100.2
– P53/DNA damage-regulated protein; TAIR: AT3G15351.1 P53/DNA damage-regulated protein; Swiss-Prot: sp|Q642A0|PDRG1_RAT p53 and DNA damage-regulated protein 1; TrEMBL-Plants: tr|K7L1B3|K7L1B3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0063100
Domains
2
LotjaGi5g1v0104200.1
– P53/DNA damage-regulated protein; TAIR: AT3G15351.1 P53/DNA damage-regulated protein; Swiss-Prot: sp|Q642A0|PDRG1_RAT p53 and DNA damage-regulated protein 1; TrEMBL-Plants: tr|A0A151R9H6|A0A151R9H6_CAJCA Uncharacterized protein; Found in the gene: LotjaGi5g1v0104200
Domains
3

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
PTHR21162 PANTHER 1 25.00