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IPR034005 is a Peptidyl-dipeptidase DCP.
<p>This entry includes the following members of peptidase subfamily M3A: peptidyl dipeptidase DCP (EC 3.4.15.5; MEROPS identifier M03.005; also known as dipeptidyl carboxypeptidase) and oligopeptidase A (OpdA; EC 3.4.24.70; MEROPS identifier M03.004). DCP releases dipeptides from the C-termini of various peptides and proteins, the smallest substrate being N-blocked tripeptides and unblocked tetrapeptides. DCP from E. coli is inhibited by the anti-hypertensive drug captopril, an inhibitor of the mammalian angiotensin converting enzyme (ACE, also called peptidyl dipeptidase A) [[cite:PUB00082131], [cite:PUB00038441]]. Oligopeptidase A (OpdA) may play a specific role in the degradation of signal peptides after they are released from precursor forms of secreted proteins. It can also cleave N-acetyl-L-Ala [[cite:PUB00082132]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: oligopeptidase A-like [Glycine max] gi|356496657|ref|XP_003517182.1| | 21 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd06456 | CDD | 1 | 100.00 |