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IPR034012

Source: InterPro

Description

IPR034012 is a Pol II subunit B9, C-terminal zinc ribbon.

<p>The C-terminal zinc ribbon domain of subunit B9 in RNA polymerase (Pol) II (RPB9) is involved in intrinsic transcript cleavage [[cite:PUB00082172]]. Eukaryote genomes are transcribed by three nuclear RNA polymerases (Pol I, II and III) that share some subunits. RPB9 is homologous to RPA12 of Pol I and RPC11 of Pol III subunits but its intrinsic cleavage activity is weaker for Pol II [[cite:PUB00056396]]. RPB9 C-terminal zinc ribbon is homologous to Pol II elongation factor TFIIS domain III [[cite:PUB00082172]]. The very weak cleavage activity of Pol II is stimulated by TFIIS. RPB9 has two zinc-binding domains separated by a flexible linker [[cite:PUB00082173]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0006379
Biological process MRNA cleavage Any process in which a pre-mRNA or mRNA molecule is cleaved at specific sites or in a regulated manner.
Subterm of

Associated Lotus transcripts 2

Transcript Name Description Predicted domains Domain count
Lj4g3v2267660.1
– PREDICTED: DNA-directed RNA polymerase II subunit RPB9 [Vitis vinifera] gi|225431922|ref|XP_002276956.1|
Domains
15
LotjaGi6g1v0257100.1
– DNA-directed RNA polymerase subunit; TAIR: AT3G16980.1 RNA polymerases M/15 Kd subunit; Swiss-Prot: sp|Q6NLH0|RPB9A_ARATH DNA-directed RNA polymerases II, IV and V subunit 9A; TrEMBL-Plants: tr|A0A1J7H2A0|A0A1J7H2A0_LUPAN Uncharacterized protein; Found in the gene: LotjaGi6g1v0257100
Domains
17

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd10508 CDD 1 50.00