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IPR034201 is a RNPS1, RNA recognition motif.
<p>This entry represents the RNA recognition motif (RRM) of RNPS1 and its eukaryotic homologues. RNPS1 was originally characterised as a general pre-mRNA splicing activator, which activates both constitutive and alternative splicing of pre-mRNA in vitro [[cite:PUB00082864]]. It has been identified as a protein component of the splicing-dependent mRNP complex, or exon-exon junction complex (EJC), and is directly involved in mRNA surveillance [[cite:PUB00082865], [cite:PUB00082866]]. Furthermore, RNPS1 is a splicing regulator whose activator function is controlled in part by CK2 (casein kinase II) protein kinase phosphorylation [[cite:PUB00082863]]. It can also function as a squamous-cell carcinoma antigen recognized by T cells-3 (SART3)-binding protein, and is involved in the regulation of mRNA splicing [[cite:PUB00082867]]. RNPS1 contains an N-terminal serine-rich (S) domain, a central RNA recognition motif (RRM), and the C-terminal arginine/serine/proline-rich (R/S/P) domain.</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | RNA-binding protein; TAIR: AT1G16610.1 arginine/serine-rich 45; Swiss-Prot: sp|Q9SEE9|SR45_ARATH Serine/arginine-rich splicing factor SR45; TrEMBL-Plants: tr|A0A151S2U5|A0A151S2U5_CAJCA RNA-binding protein with serine-rich domain 1-B; Found in the gene: LotjaGi3g1v0139900_LC | 14 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 100.00 |