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IPR035442 is a Ferredoxin--NADP reductase, plant and Cyanobacteria type.
<p>This entry includes ferredoxin--NADP reductases from plants and Cyanobacteria (blue-green algae).</p> <p>Ferredoxin reductase is a member of the flavoprotein pyridine nucleotide cytochrome reductases [[cite:PUB00002674]] (FPNCRs) that catalyse the interchange of reducing equivalents between one-electron carriers and the two-electron-carrying nicotinamide dinucleotides. Ferredoxin reductase catalyzes the final step of electron transfer to make NADPH and ATP in plant chloroplasts during photosynthesis. Other family members include plant and fungal: <ul><li>NAD(P)H:nitrate reductases [[cite:PUB00002674], [cite:PUB00005356]]</li> <li>NADH:cytochrome b5 reductases [[cite:PUB00002328]]</li> <li>NADPH:P450 reductases [[cite:PUB00005367]]</li> <li>NADPH:sulphite reductases [[cite:PUB00002509]]</li> <li>nitric oxide synthases [[cite:PUB00004098]]</li> <li>phthalate dioxygenase reductase [[cite:PUB00005007]]</li> <li>various other flavoproteins</li></ul> <p>Despite functional similarities, FPNCRs show no sequence similarity to NADPH:adrenodoxin reductases [[cite:PUB00001372]], nor to bacterial ferredoxin:NAD reductases and their homologues [[cite:PUB00003255]]. To date, structures for a number of family members have been solved: <ul> <li>Spinacia oleracea (Spinach) ferredoxin:NADP reductase [[cite:PUB00005135]]</li> <li>Burkholderia cepacia (Pseudomonas cepacia) phthalate dioxygenase reductase [[cite:PUB00005007]]</li> <li>Zea mays (Maize) nitrate reductase flavoprotein domain [[cite:PUB00005247]]</li> <li>Sus scrofa (Pig) NADH:cytochrome b5 reductase [[cite:PUB00001683]].</li> </ul> In all of them, the FAD-binding domain (N-terminal) has the topology of an anti-parallel β-barrel, while the NAD(P)-binding domain (C-terminal) has the topology of a classical pyridine dinucleotide-binding fold (i.e. a central parallel β-sheet with 2 helices on each side) [[cite:PUB00005007]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Oxidoreductase activity | Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. | ||
| Biological process | Oxidation-reduction process | A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Ferredoxin--NADP reductase; TAIR: AT5G66190.1 ferredoxin-NADP -oxidoreductase 1; Swiss-Prot: sp|P10933|FENR1_PEA Ferredoxin--NADP reductase, leaf isozyme, chloroplastic; TrEMBL-Plants: tr|A0A0R4J4B4|A0A0R4J4B4_SOYBN Ferredoxin--NADP reductase; Found in the gene: LotjaGi4g1v0128500 | 23 | ||
| – | Ferredoxin--NADP reductase; TAIR: AT5G66190.1 ferredoxin-NADP -oxidoreductase 1; Swiss-Prot: sp|P10933|FENR1_PEA Ferredoxin--NADP reductase, leaf isozyme, chloroplastic; TrEMBL-Plants: tr|A0A0R4J4B4|A0A0R4J4B4_SOYBN Ferredoxin--NADP reductase; Found in the gene: LotjaGi4g1v0128500 | 23 | ||
| – | Ferredoxin--NADP reductase; TAIR: AT4G05390.1 root FNR 1; Swiss-Prot: sp|Q41014|FENR2_PEA Ferredoxin--NADP reductase, root isozyme, chloroplastic; TrEMBL-Plants: tr|A0A151T642|A0A151T642_CAJCA Ferredoxin--NADP reductase; Found in the gene: LotjaGi6g1v0271600 | 19 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd06208 | CDD | 1 | 33.33 |