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IPR042253 is a 2,3-bisphosphoglycerate-independent phosphoglycerate mutase superfamily.
<p>This superfamily represents domain found in 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (iPGAM), it is a metalloenzyme found particularly in archaea and some eubacteria. It is responsible for the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [[cite:PUB00055097]]. It is distantly related to the iPGAM ([interpro:IPR005995]) characteristic of plants and many eubacteria. The common active site and metal-binding residues of the phosphatase domain are easily identified, but the putative phosphotransferase domain is highly diverged. These proteins are unrelated to the cofactor-dependent PGAM. Activity has been demonstrated for proteins from Methanocaldococcus jannaschii (Methanococcus jannaschii) [[cite:PUB00014447], [cite:PUB00014397]], Pyrococcus furiosus [[cite:PUB00014397]], and Sulfolobus solfataricus [[cite:PUB00014464]]. These proteins were initially misidentified as phosphonopyruvate decarboxylase.</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; TAIR: AT3G30841.1 Cofactor-independent phosphoglycerate mutase; Swiss-Prot: sp|O27628|APGM1_METTH 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 1; TrEMBL-Plants: tr|I3SP89|I3SP89_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0524100 | 12 | ||
| – | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; TAIR: AT3G30841.1 Cofactor-independent phosphoglycerate mutase; Swiss-Prot: sp|O27628|APGM1_METTH 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 1; TrEMBL-Plants: tr|I3SP89|I3SP89_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0524100 | 12 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd16011 | CDD | 1 | 50.00 |