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IPR042946 is a Carboxymethylenebutenolidase homolog.
<p>Carboxymethylenebutenolidase (CMBL) is a human homologue of Pseudomonas dienelactone hydrolase involved in the bacterial halocatechol degradation pathway. It is a cysteine hydrolase that can convert the prodrug olmesartan medoxomil into its pharmacologically active metabolite olmerstatan, an angiotensin receptor blocker, in liver and intestine [[cite:PUB00093512]].</p> <p>This entry also includes uncharacterised DLH domain-containing proteins from plants.</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | 1,4-beta-D-glucanase; TAIR: AT1G35420.2 alpha/beta-Hydrolases superfamily protein; Swiss-Prot: sp|Q96DG6|CMBL_HUMAN Carboxymethylenebutenolidase homolog; TrEMBL-Plants: tr|I1KFZ9|I1KFZ9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0337900 | 7 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| SSF53474 | SUPERFAMILY | 1 | 100.00 |