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GO:0000244

View this GO term in other databases

Overview

Field Value
Namespace Biological process
Short description Spliceosomal tri-snRNP complex assembly
Full defintion The formation of a tri-snRNP complex containing U4 and U6 (or U4atac and U6atac) snRNAs and U5 snRNAs and associated proteins. This includes reannealing of U4 and U6 (or U4atac and U6atac) snRNAs released from previous rounds of splicing to reform the U4/U6 snRNP (or U4atac/U6atac snRNP) as well as the subsequent association of the U5 snRNP with the U4/U6 snRNP (or U4atac/U6atac snRNP) to form a tri-snRNP that is ready to reassemble into another spliceosome complex.
Subterm of

Relationships

The relationship of GO:0000244 with other GO terms.

Relationship type GO terms
Is a
Regulates n.a.
Part of n.a.
Positively regulates n.a.
Negatively regulates n.a.

Ancestor tree

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Additional data

This table contains additional metadata associated with the GO entry's definition field.

Field Value
ISBN

· ISBN: 0879695897

, · pages

PMID
A spliceosomal recycling factor that reanneals U4 and U6 small nuclear ribonucleoprotein particles.Raghunathan PL, Guthrie C
Science. 1998 Feb 6; 279 (5352): 857–60.PMID: 9452384

The spliceosome removes introns from pre-messenger RNAs by a mechanism that entails extensive remodeling of RNA structure. The most conspicuous rearrangement involves disruption of 24 base pairs between U4 and U6 small nuclear RNAs (snRNAs). Here, the yeast RNA binding protein Prp24 is shown to reanneal these snRNAs. When Prp24 is absent, unpaired U4 and U6 small nuclear ribonucleoprotein particles (snRNPs) accumulate; with time, splicing becomes inhibited. Addition of purified Prp24 protein regenerates duplex U4/U6 snRNPs for new rounds of splicing. The reannealing reaction catalyzed by Prp24 proceeds more efficiently with snRNPs than with deproteinized snRNAs.

Associated Lotus transcripts 7

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

Transcript Name Description GO terms GO count
Lj1g3v3765010.1
– PREDICTED: U4/U6 small nuclear ribonucleoprotein Prp31-like isoform X2 [Cicer arietinum] gi|502100538|ref|XP_004491744.1|
GO terms
3
Lj1g3v3765010.2
– PREDICTED: U4/U6 small nuclear ribonucleoprotein Prp31-like isoform X1 [Cicer arietinum] gi|502100534|ref|XP_004491743.1|
GO terms
3
Lj3g3v3374690.1
– PREDICTED: U4/U6 small nuclear ribonucleoprotein Prp31-like [Glycine max] gi|356571467|ref|XP_003553898.1|
GO terms
3
LotjaGi1g1v0618800.1
– U4/U6 small nuclear ribonucleoprotein Prp31; TAIR: AT1G60170.1 pre-mRNA processing ribonucleoprotein binding region-containing protein; Swiss-Prot: sp|Q8RXN6|PRP31_ARATH U4/U6 small nuclear ribonucleoprotein Prp31 homolog; TrEMBL-Plants: tr|A0A0S3TBB0|A0A0S3TBB0_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0618800
GO terms
3
LotjaGi1g1v0618800.2
– U4/U6 small nuclear ribonucleoprotein Prp31; TAIR: AT1G60170.1 pre-mRNA processing ribonucleoprotein binding region-containing protein; Swiss-Prot: sp|Q8RXN6|PRP31_ARATH U4/U6 small nuclear ribonucleoprotein Prp31 homolog; TrEMBL-Plants: tr|I1MLN7|I1MLN7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0618800
GO terms
3
LotjaGi1g1v0618800.3
– U4/U6 small nuclear ribonucleoprotein Prp31; TAIR: AT1G60170.1 pre-mRNA processing ribonucleoprotein binding region-containing protein; Swiss-Prot: sp|Q8RXN6|PRP31_ARATH U4/U6 small nuclear ribonucleoprotein Prp31 homolog; TrEMBL-Plants: tr|A0A0S3TBB0|A0A0S3TBB0_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0618800
GO terms
3
LotjaGi1g1v0618800.4
– U4/U6 small nuclear ribonucleoprotein Prp31; TAIR: AT1G60170.1 pre-mRNA processing ribonucleoprotein binding region-containing protein; Swiss-Prot: sp|Q8RXN6|PRP31_ARATH U4/U6 small nuclear ribonucleoprotein Prp31 homolog; TrEMBL-Plants: tr|A0A0S3TBB0|A0A0S3TBB0_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0618800
GO terms
3

Co-occuring GO terms 1

A list of co-occurring GO terms within the L. japonicus gene space:

GO term Namespace Name Observations Saturation (%)
GO:0046540
Cellular component U4/U6 x U5 tri-snRNP complex 1 14.29