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GO:0000439

View this GO term in other databases

Overview

Field Value
Namespace Cellular component
Short description Transcription factor TFIIH core complex
Full defintion The 7 subunit core of TFIIH that is a part of either the general transcription factor holo-TFIIH or the nucleotide-excision repair factor 3 complex. In S. cerevisiae/humans the complex is composed of: Ssl2/XPB, Tfb1/p62, Tfb2/p52, Ssl1/p44, Tfb4/p34, Tfb5/p8 and Rad3/XPD.
Subterm of

Relationships

The relationship of GO:0000439 with other GO terms.

Relationship type GO terms
Is a
Regulates n.a.
Part of n.a.
Positively regulates n.a.
Negatively regulates n.a.

Ancestor tree

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Additional data

This table contains additional metadata associated with the GO entry's definition field.

Field Value
GOCkrc
PMID
Different forms of TFIIH for transcription and DNA repair: holo-TFIIH and a nucleotide excision repairosome.Svejstrup JQ, Wang Z, Feaver WJ, Wu X, Bushnell DA, Donahue TF, Friedberg EC, Kornberg RD
Cell. 1995 Jan 13; 80 (1): 21–8.PMID: 7813015

Yeast TFIIH that is active in transcription can be dissociated into three components: a 5-subunit core, the SSL2 gene product, and a complex of 47 kDa, 45 kDa, and 33 kDa polypeptides that possesses protein kinase activity directed towards the C-terminal repeat domain of RNA polymerase II. These three components can reconstitute fully functional TFIIH, and all three are required for transcription in vitro. By contrast, TFIIH that is highly active in nucleotide excision repair (NER) lacks the kinase complex and instead contains the products of all other genes known to be required for NER in yeast: RAD1, RAD2, RAD4, RAD10, and RAD14. This repairosome is not active in reconstituted transcription in vitro and is significantly more active than any of the constituent polypeptides in correcting defective repair in extracts from strains mutated in NER genes.

Associated Lotus transcripts 21

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

Transcript Name Description GO terms GO count
Lj0g3v0044669.1
– General transcription factor IIH component, related [Medicago truncatula] gi|92882353|gb|ABE86684.1|
GO terms
3
Lj0g3v0044679.1
– General transcription factor IIH component, related [Medicago truncatula] gi|92882353|gb|ABE86684.1|
GO terms
3
Lj0g3v0101459.1
– General transcription factor IIH component, related [Medicago truncatula] gi|92882353|gb|ABE86684.1|
GO terms
3
Lj1g3v0807620.1
– PREDICTED: general transcription factor IIH subunit 3-like [Glycine max] gi|356509424|ref|XP_003523449.1|
GO terms
3
Lj1g3v4107020.1
– General transcription factor IIH subunit [Medicago truncatula] gi|357509341|ref|XP_003624959.1|
GO terms
3
Lj3g3v0642530.1
– PREDICTED: probable RNA polymerase II transcription factor B subunit 1-1-like [Cicer arietinum] gi|502118052|ref|XP_004496077.1|
GO terms
3
Lj4g3v0451070.1
– PREDICTED: general transcription factor IIH subunit 4-like [Cicer arietinum] gi|502142615|ref|XP_004505045.1|
GO terms
3
Lj4g3v0451070.2
– PREDICTED: general transcription factor IIH subunit 4-like [Cicer arietinum] gi|502142615|ref|XP_004505045.1|
GO terms
3
Lj4g3v3113250.1
– General transcription factor IIH subunit [Medicago truncatula] gi|357488601|ref|XP_003614588.1|
GO terms
3
Lj5g3v1697110.1
– PREDICTED: probable RNA polymerase II transcription factor B subunit 1-1-like [Cicer arietinum] gi|502118052|ref|XP_004496077.1|
GO terms
3
Lj5g3v1697110.2
– PREDICTED: probable RNA polymerase II transcription factor B subunit 1-1-like [Cicer arietinum] gi|502118052|ref|XP_004496077.1|
GO terms
3
LotjaGi1g1v0259100.1
– General transcription factor IIH subunit, putative; TAIR: AT1G18340.1 basal transcription factor complex subunit-like protein; Swiss-Prot: sp|Q8LF41|TFB4_ARATH RNA polymerase II transcription factor B subunit 4; TrEMBL-Plants: tr|G7J304|G7J304_MEDTR General transcription factor IIH subunit, putative; Found in the gene: LotjaGi1g1v0259100
GO terms
3
LotjaGi1g1v0661700.1
– GTF2H2; TAIR: AT1G05055.1 general transcription factor II H2; Swiss-Prot: sp|Q9ZVN9|TF2H2_ARATH General transcription factor IIH subunit 2; TrEMBL-Plants: tr|A0A1J7IMI8|A0A1J7IMI8_LUPAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0661700
GO terms
3
LotjaGi1g1v0661700.2
– GTF2H2; TAIR: AT1G05055.1 general transcription factor II H2; Swiss-Prot: sp|Q9ZVN9|TF2H2_ARATH General transcription factor IIH subunit 2; TrEMBL-Plants: tr|G7L5Y2|G7L5Y2_MEDTR General transcription factor IIH subunit 2; Found in the gene: LotjaGi1g1v0661700
GO terms
3
LotjaGi1g1v0661700.3
– GTF2H2; TAIR: AT1G05055.1 general transcription factor II H2; Swiss-Prot: sp|Q9ZVN9|TF2H2_ARATH General transcription factor IIH subunit 2; TrEMBL-Plants: tr|A0A1J7IMI8|A0A1J7IMI8_LUPAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0661700
GO terms
3
LotjaGi4g1v0055200.1
– Transcription factor; TAIR: AT4G17020.1 transcription factor-like protein; Swiss-Prot: sp|Q680U9|TFB2_ARATH RNA polymerase II transcription factor B subunit 2; TrEMBL-Plants: tr|G7ZZ96|G7ZZ96_MEDTR General transcription factor IIH protein; Found in the gene: LotjaGi4g1v0055200
GO terms
3
LotjaGi4g1v0055200.2
– Transcription factor; TAIR: AT4G17020.3 transcription factor-like protein; Swiss-Prot: sp|Q680U9|TFB2_ARATH RNA polymerase II transcription factor B subunit 2; TrEMBL-Plants: tr|A0A1J7GYK6|A0A1J7GYK6_LUPAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0055200
GO terms
3
LotjaGi4g1v0055200.3
– Transcription factor; TAIR: AT4G17020.1 transcription factor-like protein; Swiss-Prot: sp|Q680U9|TFB2_ARATH RNA polymerase II transcription factor B subunit 2; TrEMBL-Plants: tr|A0A1J7GYK6|A0A1J7GYK6_LUPAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0055200
GO terms
3
LotjaGi4g1v0055200.4
– Transcription factor; TAIR: AT4G17020.1 transcription factor-like protein; Swiss-Prot: sp|Q680U9|TFB2_ARATH RNA polymerase II transcription factor B subunit 2; TrEMBL-Plants: tr|A0A0R0J5X6|A0A0R0J5X6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0055200
GO terms
3
LotjaGi4g1v0055200.5
– Transcription factor; TAIR: AT4G17020.1 transcription factor-like protein; Swiss-Prot: sp|Q680U9|TFB2_ARATH RNA polymerase II transcription factor B subunit 2; TrEMBL-Plants: tr|G7ZZ96|G7ZZ96_MEDTR General transcription factor IIH protein; Found in the gene: LotjaGi4g1v0055200
GO terms
3
LotjaGi5g1v0258200.2
– BSD domain (BTF2-like transcription factors, Synapse-associated proteins and DOS2-like proteins); TAIR: AT1G55750.1 BSD domain (BTF2-like transcription factors, Synapse-associated proteins and DOS2-like proteins); Swiss-Prot: sp|Q3ECP0|TFB1A_ARATH Probable RNA polymerase II transcription factor B subunit 1-1; TrEMBL-Plants: tr|I1LCH7|I1LCH7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0258200
GO terms
3

Co-occuring GO terms 1

A list of co-occurring GO terms within the L. japonicus gene space:

GO term Namespace Name Observations Saturation (%)
GO:0006351
Biological process Transcription, DNA-templated 1 4.76