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GO:0000724

View this GO term in other databases

Overview

Field Value
Namespace Biological process
Short description Double-strand break repair via homologous recombination
Full defintion The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.
Subterm of

Relationships

The relationship of GO:0000724 with other GO terms.

Relationship type GO terms
Is a
Regulates n.a.
Part of n.a.
Positively regulates n.a.
Negatively regulates n.a.

Ancestor tree

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Additional data

This table contains additional metadata associated with the GO entry's definition field.

Field Value
GOCelh
PMID
Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae.Pâques F, Haber JE
Microbiol Mol Biol Rev. 1999 Jun; 63 (2): 349–404.PMID: 10357855

The budding yeast Saccharomyces cerevisiae has been the principal organism used in experiments to examine genetic recombination in eukaryotes. Studies over the past decade have shown that meiotic recombination and probably most mitotic recombination arise from the repair of double-strand breaks (DSBs). There are multiple pathways by which such DSBs can be repaired, including several homologous recombination pathways and still other nonhomologous mechanisms. Our understanding has also been greatly enriched by the characterization of many proteins involved in recombination and by insights that link aspects of DNA repair to chromosome replication. New molecular models of DSB-induced gene conversion are presented. This review encompasses these different aspects of DSB-induced recombination in Saccharomyces and attempts to relate genetic, molecular biological, and biochemical studies of the processes of DNA repair and recombination.

Associated Lotus transcripts 25

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

Transcript Name Description GO terms GO count
Lj0g3v0001919.1
– Protein BRCA2-like B [Arabidopsis thaliana] gi|42567571|ref|NP_195783.3|
GO terms
2
Lj0g3v0089779.1
– Protein BRCA2-like B [Arabidopsis thaliana] gi|42567571|ref|NP_195783.3|
GO terms
2
Lj0g3v0257079.1
– PREDICTED: DNA repair protein RAD51 homolog 2-like isoform X1 [Cicer arietinum] gi|502082384|ref|XP_004487150.1|
GO terms
4
Lj0g3v0257079.2
– PREDICTED: DNA repair protein RAD51 homolog 2-like isoform X1 [Cicer arietinum] gi|502082384|ref|XP_004487150.1|
GO terms
4
Lj0g3v0257079.3
– PREDICTED: DNA repair protein RAD51 homolog 2-like isoform X1 [Cicer arietinum] gi|502082384|ref|XP_004487150.1|
GO terms
4
Lj0g3v0268089.2
– PREDICTED: E3 SUMO-protein ligase MMS21-like [Cicer arietinum] gi|502183399|ref|XP_004517129.1|
GO terms
3
Lj0g3v0268089.3
– PREDICTED: E3 SUMO-protein ligase MMS21-like [Cicer arietinum] gi|502183399|ref|XP_004517129.1|
GO terms
3
Lj3g3v0824810.2
– PREDICTED: structural maintenance of chromosomes protein 5-like [Glycine max] gi|356576425|ref|XP_003556332.1|
GO terms
4
Lj3g3v0824810.3
– PREDICTED: structural maintenance of chromosomes protein 5-like [Glycine max] gi|356576425|ref|XP_003556332.1|
GO terms
4
Lj3g3v0824870.1
– PREDICTED: structural maintenance of chromosomes protein 5-like [Glycine max] gi|356576425|ref|XP_003556332.1|
GO terms
4
Lj3g3v3724440.1
– PREDICTED: structural maintenance of chromosomes protein 6-like [Cicer arietinum] gi|502168978|ref|XP_004514508.1|
GO terms
3
Lj4g3v2215340.1
– PREDICTED: DNA repair protein RAD51 homolog 1-like [Cicer arietinum] gi|502150634|ref|XP_004508049.1|
GO terms
6
LotjaGi3g1v0119400_LC.1
– Structural maintenance of chromosomes family protein; TAIR: AT5G15920.1 structural maintenance of chromosomes 5; Swiss-Prot: sp|Q9LFS8|SMC5_ARATH Structural maintenance of chromosomes protein 5; TrEMBL-Plants: tr|A0A151TWB4|A0A151TWB4_CAJCA Structural maintenance of chromosomes protein 5; Found in the gene: LotjaGi3g1v0119400_LC
GO terms
4
LotjaGi3g1v0119400_LC.3
– Structural maintenance of chromosomes family protein; TAIR: AT5G15920.1 structural maintenance of chromosomes 5; Swiss-Prot: sp|Q9LFS8|SMC5_ARATH Structural maintenance of chromosomes protein 5; TrEMBL-Plants: tr|A0A0S3QXY9|A0A0S3QXY9_PHAAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0119400_LC
GO terms
4
LotjaGi3g1v0119400_LC.4
– Structural maintenance of chromosomes family protein; TAIR: AT5G15920.1 structural maintenance of chromosomes 5; Swiss-Prot: sp|Q9LFS8|SMC5_ARATH Structural maintenance of chromosomes protein 5; TrEMBL-Plants: tr|G7JE71|G7JE71_MEDTR Structural maintenance-like chromosomes-protein; Found in the gene: LotjaGi3g1v0119400_LC
GO terms
4
LotjaGi3g1v0119500_LC.1
– Structural maintenance of chromosomes family protein; TAIR: AT5G15920.1 structural maintenance of chromosomes 5; Swiss-Prot: sp|Q9LFS8|SMC5_ARATH Structural maintenance of chromosomes protein 5; TrEMBL-Plants: tr|G7J0X6|G7J0X6_MEDTR Structural maintenance-like chromosomes-protein; Found in the gene: LotjaGi3g1v0119500_LC
GO terms
4
LotjaGi3g1v0119700.1
– Structural maintenance of chromosomes family protein; TAIR: AT5G15920.1 structural maintenance of chromosomes 5; Swiss-Prot: sp|Q9LFS8|SMC5_ARATH Structural maintenance of chromosomes protein 5; TrEMBL-Plants: tr|V7CP68|V7CP68_PHAVU Uncharacterized protein; Found in the gene: LotjaGi3g1v0119700
GO terms
4
LotjaGi3g1v0269600.1
– DNA repair RAD51-like protein; TAIR: AT2G28560.2 DNA repair (Rad51) family protein; Swiss-Prot: sp|Q9SK02|RA51B_ARATH DNA repair protein RAD51 homolog 2; TrEMBL-Plants: tr|A0A0S3SGI1|A0A0S3SGI1_PHAAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0269600
GO terms
4
LotjaGi3g1v0269600.2
– DNA repair RAD51-like protein; TAIR: AT2G28560.2 DNA repair (Rad51) family protein; Swiss-Prot: sp|Q9SK02|RA51B_ARATH DNA repair protein RAD51 homolog 2; TrEMBL-Plants: tr|A0A0S3SGI1|A0A0S3SGI1_PHAAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0269600
GO terms
4
LotjaGi3g1v0525200.1
– DNA repair protein XRCC2 like; TAIR: AT5G64520.5 homolog of X-ray repair cross complementing 2 (XRCC2); Swiss-Prot: sp|Q682D3|XRCC2_ARATH DNA repair protein XRCC2 homolog; TrEMBL-Plants: tr|A0A072UXF4|A0A072UXF4_MEDTR X-ray repair cross complementing 2 (XRCC2)-like protein, putative; Found in the gene: LotjaGi3g1v0525200
GO terms
4
LotjaGi3g1v0525200.2
– DNA repair protein XRCC2 like; TAIR: AT5G64520.5 homolog of X-ray repair cross complementing 2 (XRCC2); Swiss-Prot: sp|Q682D3|XRCC2_ARATH DNA repair protein XRCC2 homolog; TrEMBL-Plants: tr|A0A072UXF4|A0A072UXF4_MEDTR X-ray repair cross complementing 2 (XRCC2)-like protein, putative; Found in the gene: LotjaGi3g1v0525200
GO terms
4
LotjaGi3g1v0552100.1
– Structural maintenance of chromosomes family protein; TAIR: AT5G07660.1 structural maintenance of chromosomes 6A; Swiss-Prot: sp|Q9FLR5|SMC6A_ARATH Structural maintenance of chromosomes protein 6A; TrEMBL-Plants: tr|A0A0S3SER5|A0A0S3SER5_PHAAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0552100
GO terms
3
LotjaGi3g1v0555400.1
– Cobalt ion binding; TAIR: AT1G71310.1 cobalt ion binding protein; Swiss-Prot: sp|Q9FVV7|RD521_ARATH DNA repair RAD52-like protein 1, mitochondrial; TrEMBL-Plants: tr|I3T569|I3T569_LOTJA Uncharacterized protein; Found in the gene: LotjaGi3g1v0555400
GO terms
2
LotjaGi4g1v0319500.1
– DNA repair protein RAD51 like 1; TAIR: AT5G20850.1 RAS associated with diabetes protein 51; Swiss-Prot: sp|P94102|RAD51_ARATH DNA repair protein RAD51 homolog 1; TrEMBL-Plants: tr|A0A151SSM0|A0A151SSM0_CAJCA DNA repair protein RAD51 isogeny 1; Found in the gene: LotjaGi4g1v0319500
GO terms
6
LotjaGi5g1v0366600.1
– Cobalt ion-binding protein; TAIR: AT5G47870.1 cobalt ion-binding protein; Swiss-Prot: sp|Q9FIJ4|RD522_ARATH DNA repair RAD52-like protein 2, chloroplastic; TrEMBL-Plants: tr|I3T4N4|I3T4N4_LOTJA Uncharacterized protein; Found in the gene: LotjaGi5g1v0366600
GO terms
2

Co-occuring GO terms 1

A list of co-occurring GO terms within the L. japonicus gene space:

GO term Namespace Name Observations Saturation (%)
GO:0003677
Molecular function DNA binding 1 4.00