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GO:0001004

View this GO term in other databases

Overview

Field Value
Namespace Molecular function
Short description RNA polymerase III transcription regulator recruiting activity
Full defintion Initiating the assembly of the RNA polymerase III pre-initiation complex by binding to a control sequence in the intragenic region. This allows to recruit TFIIIB to the DNA at a site centered approximately 26 base pairs upstream of the start site of transcription. For tRNA genes, TFIIIC first associates with DNA, and then recruits TFIIIB. For 5S rRNA genes, TFIIIA binds to DNA first, followed by TFIIIC, which then recruits TFIIIB.
Subterm of

Relationships

The relationship of GO:0001004 with other GO terms.

Relationship type GO terms
Is a
Regulates n.a.
Part of n.a.
Positively regulates n.a.
Negatively regulates n.a.

Ancestor tree

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Additional data

This table contains additional metadata associated with the GO entry's definition field.

Field Value
GOCtxnOH-2018
WikipediaRNA_polymerase_III
PMID
Transcription by RNA polymerase III: insights into mechanism and regulation.Turowski TW, Tollervey D
Biochem Soc Trans. 2016 Oct 15; 44 (5): 1367–1375.PMID: 27911719

The highly abundant, small stable RNAs that are synthesized by RNA polymerase III (RNAPIII) have key functional roles, particularly in the protein synthesis apparatus. Their expression is metabolically demanding, and is therefore coupled to changing demands for protein synthesis during cell growth and division. Here, we review the regulatory mechanisms that control the levels of RNAPIII transcripts and discuss their potential physiological relevance. Recent analyses have revealed differential regulation of tRNA expression at all steps on its biogenesis, with significant deregulation of mature tRNAs in cancer cells.

Associated Lotus transcripts 1

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

Transcript Name Description GO terms GO count
LotjaGi1g1v0187300.1
– General transcription factor 3C polypeptide 3; TAIR: AT1G17680.1 tetratricopeptide repeat (TPR)-containing protein; Swiss-Prot: sp|Q9Y5Q9|TF3C3_HUMAN General transcription factor 3C polypeptide 3; TrEMBL-Plants: tr|A0A151TN13|A0A151TN13_CAJCA Uncharacterized protein; Found in the gene: LotjaGi1g1v0187300
GO terms
2

Co-occuring GO terms 1

A list of co-occurring GO terms within the L. japonicus gene space:

GO term Namespace Name Observations Saturation (%)
GO:0006383
Biological process Transcription by RNA polymerase III 1 100.00