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GO:0002218
Overview
| Field | Value |
|---|---|
| Namespace | Biological process |
| Short description | Activation of innate immune response |
| Full defintion | Any process that initiates an innate immune response. Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. Examples of this process include activation of the hypersensitive response of Arabidopsis thaliana and activation of any NOD or TLR signaling pathway in vertebrate species. |
| Subterm of |
Relationships
The relationship of GO:0002218 with other GO terms.
| Relationship type | GO terms |
|---|---|
| Is a | |
| Regulates | n.a. |
| Part of | n.a. |
| Positively regulates | n.a. |
| Negatively regulates | n.a. |
Ancestor tree
A force layout showing the ancestor tree for GO:0002218, and its immediate children. If you wish to explore the tree dynamically, please use the GO Explorer.
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Additional data
This table contains additional metadata associated with the GO entry's definition field.
| Field | Value |
|---|---|
| GOC | mtg_sensu |
| PMID | Are innate immune signaling pathways in plants and animals conserved? Nat Immunol. 2005 Oct; 6 (10): 973–9.PMID: 16177805 Although adaptive immunity is unique to vertebrates, the innate immune response seems to have ancient origins. Common features of innate immunity in vertebrates, invertebrate animals and plants include defined receptors for microbe-associated molecules, conserved mitogen-associated protein kinase signaling cascades and the production of antimicrobial peptides. It is commonly reported that these similarities in innate immunity represent a process of divergent evolution from an ancient unicellular eukaryote that pre-dated the divergence of the plant and animal kingdoms. However, at present, data suggest that the seemingly analogous regulatory modules used in plant and animal innate immunity are a consequence of convergent evolution and reflect inherent constraints on how an innate immune system can be constructed. |
| ISBN | |
| GO_REF | 0000022 |
Associated Lotus transcripts
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .