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Field | Value |
---|---|
Namespace | Molecular function |
Short description | Nuclear export signal receptor activity |
Full defintion | Combining with a nuclear export signal (NES) on a cargo to be transported, to mediate transport of a the cargo through the nuclear pore, from the nuclear lumen to the cytoplasm. The cargo can be either a RNA or a protein. |
Subterm of |
The relationship of GO:0005049 with other GO terms.
Relationship type | GO terms |
---|---|
Is a | |
Regulates | n.a. |
Part of | n.a. |
Positively regulates | n.a. |
Negatively regulates | n.a. |
A force layout showing the ancestor tree for GO:0005049, and its immediate children. If you wish to explore the tree dynamically, please use the GO Explorer.
This table contains additional metadata associated with the GO entry's definition field.
Field | Value |
---|---|
GOC | vw |
Wikipedia | Nuclear_transport |
PMID | The molecular mechanism for nuclear transport and its application. Anat Cell Biol. 2017 Jun; 50 (2): 77–85.PMID: 28713609 Transportation between the cytoplasm and the nucleoplasm is critical for many physiological and pathophysiological processes including gene expression, signal transduction, and oncogenesis. So, the molecular mechanism for the transportation needs to be studied not only to understand cell physiological processes but also to develop new diagnostic and therapeutic targets. Recent progress in the research of the nuclear transportation (import and export) via nuclear pore complex and four important factors affecting nuclear transport (nucleoporins, Ran, karyopherins, and nuclear localization signals/nuclear export signals) will be discussed. Moreover, the clinical significance of nuclear transport and its application will be reviewed. This review will provide some critical insight for the molecular design of therapeutics which need to be targeted inside the nucleus. |
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
Transcript | Name | Description | GO terms | GO count |
---|---|---|---|---|
– | Exportin-1 [Medicago truncatula] gi|357481145|ref|XP_003610858.1| | 1 | ||
– | PREDICTED: exportin-4-like isoform X1 [Cicer arietinum] gi|502113754|ref|XP_004494748.1| | 1 | ||
– | PREDICTED: exportin-1-like isoform 2 [Glycine max] gi|356538753|ref|XP_003537865.1| | 1 | ||
– | PREDICTED: exportin-1-like isoform 1 [Glycine max] gi|356538463|ref|XP_003537723.1| | 1 | ||
– | PREDICTED: exportin-1-like isoform 1 [Glycine max] gi|356538463|ref|XP_003537723.1| | 1 | ||
– | Exportin-4; TAIR: AT3G04490.2 exportin-4 protein; Swiss-Prot: sp|Q499Y0|XPO4_XENLA Exportin-4; TrEMBL-Plants: tr|K7N067|K7N067_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0785100 | 1 | ||
– | Exportin-4; TAIR: AT3G04490.2 exportin-4 protein; Swiss-Prot: sp|Q5ZMR9|XPO4_CHICK Exportin-4; TrEMBL-Plants: tr|K7N067|K7N067_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0785100 | 1 | ||
– | Exportin-4; TAIR: AT3G04490.2 exportin-4 protein; Swiss-Prot: sp|Q499Y0|XPO4_XENLA Exportin-4; TrEMBL-Plants: tr|K7N067|K7N067_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0785100 | 1 | ||
– | Exportin-4; TAIR: AT3G04490.2 exportin-4 protein; Swiss-Prot: sp|Q499Y0|XPO4_XENLA Exportin-4; TrEMBL-Plants: tr|K7N067|K7N067_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0785100 | 1 | ||
– | Exportin-1; TAIR: AT5G17020.1 exportin 1A; Swiss-Prot: sp|Q9SMV6|XPO1A_ARATH Protein EXPORTIN 1A; TrEMBL-Plants: tr|A0A0S3SEC4|A0A0S3SEC4_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0449000 | 1 | ||
– | Exportin-1; TAIR: AT5G17020.1 exportin 1A; Swiss-Prot: sp|Q9SMV6|XPO1A_ARATH Protein EXPORTIN 1A; TrEMBL-Plants: tr|A0A0S3SEC4|A0A0S3SEC4_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0449000 | 1 | ||
– | Exportin-1; TAIR: AT5G17020.1 exportin 1A; Swiss-Prot: sp|Q9SMV6|XPO1A_ARATH Protein EXPORTIN 1A; TrEMBL-Plants: tr|A0A0S3SEC4|A0A0S3SEC4_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0449000 | 1 | ||
– | Exportin-1; TAIR: AT5G17020.2 exportin 1A; Swiss-Prot: sp|Q9SMV6|XPO1A_ARATH Protein EXPORTIN 1A; TrEMBL-Plants: tr|A0A0L9V7V7|A0A0L9V7V7_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0449000 | 1 | ||
– | Exportin-1; TAIR: AT5G17020.1 exportin 1A; Swiss-Prot: sp|Q9SMV6|XPO1A_ARATH Protein EXPORTIN 1A; TrEMBL-Plants: tr|A0A0S3SEC4|A0A0S3SEC4_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0449000 | 1 | ||
– | Exportin-1; TAIR: AT5G17020.1 exportin 1A; Swiss-Prot: sp|Q9SMV6|XPO1A_ARATH Protein EXPORTIN 1A; TrEMBL-Plants: tr|I1LII4|I1LII4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0538500 | 1 | ||
– | Exportin-1; TAIR: AT5G17020.1 exportin 1A; Swiss-Prot: sp|Q9SMV6|XPO1A_ARATH Protein EXPORTIN 1A; TrEMBL-Plants: tr|I1LII4|I1LII4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0538500 | 1 |
A list of co-occurring GO terms within the L. japonicus gene space:
GO term | Namespace | Name | Observations | Saturation (%) |
---|---|---|---|---|
Molecular function | Nuclear export signal receptor activity | 1 | 6.25 |