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GO:0005905
Overview
| Field | Value |
|---|---|
| Namespace | Cellular component |
| Short description | Clathrin-coated pit |
| Full defintion | A part of the endomembrane system in the form of an invagination of a membrane upon which a clathrin coat forms, and that can be converted by vesicle budding into a clathrin-coated vesicle. Coated pits form on the plasma membrane, where they are involved in receptor-mediated selective transport of many proteins and other macromolecules across the cell membrane, in the trans-Golgi network, and on some endosomes. |
| Subterm of |
Relationships
The relationship of GO:0005905 with other GO terms.
| Relationship type | GO terms |
|---|---|
| Is a | |
| Regulates | n.a. |
| Part of | |
| Positively regulates | n.a. |
| Negatively regulates | n.a. |
Ancestor tree
A force layout showing the ancestor tree for GO:0005905, and its immediate children. If you wish to explore the tree dynamically, please use the GO Explorer.
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Additional data
This table contains additional metadata associated with the GO entry's definition field.
| Field | Value |
|---|---|
| GOC | mah |
| PMID | Rhythmic cycle of clathrin-coated pit formation at the trans-golgi network in human MDA-MB-435 cells. Biosci Biotechnol Biochem. 2007 Feb; 71 (2): 571–4.PMID: 17284835 We studied the in vivo dynamics of enhanced green fluorescent protein-tagged clathrin light chain a (GFP-CLCa) at the trans-Golgi network (TGN) in MDA-MB-435 cells. The intensity of fluorescence signals of GFP-CLCa periodically increased and decreased at the TGN approximately every 100 s. This suggests that the formation of clathrin-coated pits occurs synchronously and periodically at the TGN. |
| ISBN | |
| NIF_Subcellular | sao1969557946 |
Associated Lotus transcripts
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .