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GO:0007186

View this GO term in other databases

Overview

Field Value
Namespace Biological process
Short description G protein-coupled receptor signaling pathway
Full defintion A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576).
Subterm of

Relationships

The relationship of GO:0007186 with other GO terms.

Relationship type GO terms
Is a
Regulates n.a.
Part of n.a.
Positively regulates n.a.
Negatively regulates n.a.

Ancestor tree

A force layout showing the ancestor tree for GO:0007186, and its immediate children. If you wish to explore the tree dynamically, please use the GO Explorer.

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Controls

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Additional data

This table contains additional metadata associated with the GO entry's definition field.

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Developed with the end-user in mind, Lotus Base is an user-friendly web interface that brings together various resources, tools and datasets available for the model legume Lotus japonicus. We aim to make access to these data easy for researchers, scientists and members of the public across the world.

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Field Value
GOCmah
WikipediaG_protein-coupled_receptor