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GO:0009341

Overview

Field Value
Namespace Cellular component
Short description Beta-galactosidase complex
Full defintion A protein complex that possesses beta-galactosidase activity, i.e. catalyzes the hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides. In E. coli, the complex is a homotetramer; dimeric and hexameric beta-galactosidase complexes have been observed in other species.
Subterm of

Relationships

The relationship of GO:0009341 with other GO terms.

Relationship type GO terms
Is a
Regulates n.a.
Part of n.a.
Positively regulates n.a.
Negatively regulates n.a.

Ancestor tree

A force layout showing the ancestor tree for GO:0009341, and its immediate children. If you wish to explore the tree dynamically, please use the GO Explorer.

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Additional data

This table contains additional metadata associated with the GO entry's definition field.

Field Value
EC3.2.1.23
PMID
The structure of E. coli beta-galactosidase.
C R Biol. ; 328 (6): 549–56.PMID: 15950161

E. coli beta-galactosidase is a tetramer of four identical 1023-amino acid chains. Each chain consists of five domains, the third of which is an eight-stranded alpha/beta barrel that comprises much of the active site. This site does, however, include elements from other domains and other subunits. The N-terminal region of the polypeptide chains help form one of the subunit interfaces. Taken together these features provide a structural basis for the well-known property of alpha-complementation. Catalytic activity proceeds via the formation of a covalent galactosyl intermediate with Glu537, and includes 'shallow' and 'deep' modes of substrate binding.

BRENDA3.2.1.2

Associated Lotus transcripts 2

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

Transcript Name Description GO terms GO count
PREDICTED: beta-galactosidase-like [Glycine max] gi|356548875|ref|XP_003542824.1| 3
Beta-galactosidase; TAIR: AT3G54440.1 glycoside hydrolase family 2 protein; Swiss-Prot: sp|A5F5U6|BGAL_VIBC3 Beta-galactosidase; TrEMBL-Plants: tr|I1M0S4|I1M0S4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0318400 3

Co-occuring GO terms 1

A list of co-occurring GO terms within the L. japonicus gene space:

GO term Namespace Name Observations Saturation (%)
Cellular component Beta-galactosidase complex 1 50.00