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GO:0016279

View this GO term in other databases

Overview

Field Value
Namespace Molecular function
Short description Protein-lysine N-methyltransferase activity
Full defintion Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue in a protein substrate.
Subterm of

Relationships

The relationship of GO:0016279 with other GO terms.

Relationship type GO terms
Is a
Regulates n.a.
Part of n.a.
Positively regulates n.a.
Negatively regulates n.a.

Ancestor tree

A force layout showing the ancestor tree for GO:0016279, and its immediate children. If you wish to explore the tree dynamically, please use the GO Explorer.

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Additional data

This table contains additional metadata associated with the GO entry's definition field.

Field Value
PMID
Protein N-methyltransferase assays in the study of gene transcription.Schneider R, Bannister AJ
Methods. 2002 Mar; 26 (3): 226–32.PMID: 12054878

Protein N-methylation has recently emerged as a major mechanism involved in regulating gene transcription and epigenetic inheritance. Transcriptional coactivators and corepressors have both been shown to associate with protein N-methyltransferases. These enzymes methylate arginine or lysine residues within histones as well as other proteins, such as transcription factors. Here, we discuss the recent advances in our understanding of protein methylation and its involvement in gene expression. Protocols are presented for studying transcriptionally relevant protein methylation.

Associated Lotus transcripts 5

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

Transcript Name Description GO terms GO count
Lj0g3v0132279.2
– PREDICTED: ribosomal N-lysine methyltransferase 3-like [Cicer arietinum] gi|502116507|ref|XP_004495465.1|
GO terms
2
Lj0g3v0333629.1
– PREDICTED: N(6)-adenine-specific DNA methyltransferase 2-like [Cicer arietinum] gi|502141459|ref|XP_004504516.1|
GO terms
1
Lj0g3v0333629.2
– PREDICTED: N(6)-adenine-specific DNA methyltransferase 2-like [Cicer arietinum] gi|502141459|ref|XP_004504516.1|
GO terms
1
LotjaGi5g1v0112000.1
– Protein-lysine N-methyltransferase; TAIR: AT3G58470.1 nucleic acid binding / methyltransferase; Swiss-Prot: sp|Q9CY45|N6MT2_MOUSE Protein-lysine N-methyltransferase N6amt2; TrEMBL-Plants: tr|A0A0R0IGD8|A0A0R0IGD8_SOYBN Protein-lysine N-methyltransferase GLYMA_09G103300; Found in the gene: LotjaGi5g1v0112000
GO terms
1
LotjaGi5g1v0196700.1
– SET-domain protein lysine methyltransferase family protein; TAIR: AT3G56570.1 SET domain-containing protein; Swiss-Prot: sp|P38222|RKM3_YEAST Ribosomal lysine N-methyltransferase 3; TrEMBL-Plants: tr|V7BDL1|V7BDL1_PHAVU Uncharacterized protein; Found in the gene: LotjaGi5g1v0196700
GO terms
2

Co-occuring GO terms 1

A list of co-occurring GO terms within the L. japonicus gene space:

GO term Namespace Name Observations Saturation (%)
GO:0018026
Biological process Peptidyl-lysine monomethylation 1 20.00