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GO:0016558
Overview
| Field | Value |
|---|---|
| Namespace | Biological process |
| Short description | Protein import into peroxisome matrix |
| Full defintion | The import of proteins into the peroxisomal matrix. A peroxisome targeting signal (PTS) binds to a soluble receptor protein in the cytosol, and the resulting complex then binds to a receptor protein in the peroxisome membrane and is imported. The cargo protein is then released into the peroxisome matrix. |
| Subterm of |
Relationships
The relationship of GO:0016558 with other GO terms.
| Relationship type | GO terms |
|---|---|
| Is a | |
| Regulates | n.a. |
| Part of | n.a. |
| Positively regulates | n.a. |
| Negatively regulates | n.a. |
Ancestor tree
A force layout showing the ancestor tree for GO:0016558, and its immediate children. If you wish to explore the tree dynamically, please use the GO Explorer.
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Additional data
This table contains additional metadata associated with the GO entry's definition field.
| Field | Value |
|---|---|
| ISBN | Molecular Cell Biology Scientific American Library, 2000 · 1190 pages With its acclaimed author team, cutting-edge content, emphasis on medical relevance, and coverage based on landmark experiments, "Molecular Cell Biology" has justly earned an impeccable reputation as an authoritative and exciting text. The new Sixth Edition features two new coauthors, expanded coverage of immunology and development, and new media tools for students and instructors. |
| PMID | Opinion: peroxisomal-protein import: is it really that complex? Nat Rev Mol Cell Biol. 2002 May; 3 (5): 382–9.PMID: 11988772 Peroxisomal enzymes are synthesized in the cytoplasm and imported post-translationally across the peroxisome membrane. Unlike other organelles with a sealed membrane, peroxisomes can import folded enzymes, and they seem to lack intraperoxisomal chaperones. Here, we propose a mechanistic model for the early steps in peroxisomal-matrix-enzyme import, which might help to explain the unusual features of this process. |
Associated Lotus transcripts
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .