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GO:0030124

View this GO term in other databases

Overview

Field Value
Namespace Cellular component
Short description AP-4 adaptor complex
Full defintion An AP-type membrane coat adaptor complex that consists of beta4, epsilon, mu4 and sigma4 subunits and is found associated with membranes in the trans-Golgi network; it is not clear whether AP-4 forms clathrin coats in vivo.
Subterm of

Relationships

The relationship of GO:0030124 with other GO terms.

Relationship type GO terms
Is a
Regulates n.a.
Part of n.a.
Positively regulates n.a.
Negatively regulates n.a.

Ancestor tree

A force layout showing the ancestor tree for GO:0030124, and its immediate children. If you wish to explore the tree dynamically, please use the GO Explorer.

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Additional data

This table contains additional metadata associated with the GO entry's definition field.

Field Value
GOCmah
PMID
Adaptors for clathrin-mediated traffic.Kirchhausen T
Annu Rev Cell Dev Biol. 1999; 15 (): 705–32.PMID: 10611976

Clathrin-based systems are responsible for a large portion of vesicular traffic originating from the plasma membrane and the trans-Golgi network that reaches the endosomal compartment. The assembly of cytosolic clathrin forms the scaffold required for the local deformation of the membrane and for the formation of coated pits and vesicles. In this process, clathrin interacts in a coordinated fashion with a large number of protein partners. A subset designated clathrin adaptors links integral membrane proteins to the clathrin coat, a process that results in the recruitment of specific cargo proteins to the budding vesicle. This review focuses on the most recent advances dealing with the molecular basis for sorting by clathrin adaptors.

Associated Lotus transcripts 1

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

Transcript Name Description GO terms GO count
LotjaGi4g1v0142400.1
– AP-4 complex subunit epsilon; TAIR: AT1G31730.1 Adaptin family protein; Swiss-Prot: sp|Q8L7A9|AP4E_ARATH AP-4 complex subunit epsilon; TrEMBL-Plants: tr|G7L7U1|G7L7U1_MEDTR AP-4 complex subunit epsilon; Found in the gene: LotjaGi4g1v0142400
GO terms
2

Co-occuring GO terms 1

A list of co-occurring GO terms within the L. japonicus gene space:

GO term Namespace Name Observations Saturation (%)
GO:0030124
Cellular component AP-4 adaptor complex 1 100.00