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GO:0032040

Overview

Field Value
Namespace Cellular component
Short description Small-subunit processome
Full defintion A large ribonucleoprotein complex that is an early preribosomal complex. In S. cerevisiae, it has a size of 80S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins.
Subterm of

Relationships

The relationship of GO:0032040 with other GO terms.

Relationship type GO terms
Is a
Regulates n.a.
Part of n.a.
Positively regulates n.a.
Negatively regulates n.a.

Ancestor tree

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Additional data

This table contains additional metadata associated with the GO entry's definition field.

Field Value
GOCvw
PMID
The small-subunit processome is a ribosome assembly intermediate.
Eukaryot Cell. ; 3 (6): 1619–26.PMID: 15590835

The small-subunit (SSU) processome is a large ribonucleoprotein required for the biogenesis of the 18S rRNA and likely corresponds to the terminal knobs visualized by electron microscopy on the 5' end of nascent rRNAs. The original purification of the SSU processome of Saccharomyces cerevisiae resulted in the identification of 28 proteins. Here, we characterize 12 additional protein components, including five small-ribosomal-subunit proteins (Rps4, Rps6, Rps7, Rps9, and Rps14) that had previously been copurified. Our multiple criteria for including a component as a bona fide SSU processome component included coimmunoprecipitation with Mpp10 (an SSU processome component), the U3 snoRNA, and the anticipated pre-rRNAs. Importantly, the association of specific ribosomal proteins with the SSU processome suggests that the SSU processome has roles in both pre-rRNA processing and ribosome assembly. These ribosomal proteins may be analogous to the primary or secondary RNA binding proteins first described in bacterial in vitro ribosome assembly maps. In addition to the ribosomal proteins and based on the same experimental approach, we found seven other proteins (Utp18, Noc4, Utp20, Utp21, Utp22, Emg1, and Krr1) to be bona fide SSU processome proteins.

Associated Lotus transcripts 25

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

Transcript Name Description GO terms GO count
PREDICTED: rRNA-processing protein FCF1 homolog [Glycine max] gi|356543662|ref|XP_003540279.1| 1
PREDICTED: U3 small nucleolar RNA-associated protein 14 homolog B-like [Glycine max] gi|356503904|ref|XP_003520740.1| 2
PREDICTED: rRNA-processing protein FCF1 homolog [Glycine max] gi|356543662|ref|XP_003540279.1| 1
PREDICTED: WD repeat-containing protein 36-like [Glycine max] gi|356527435|ref|XP_003532316.1| 2
PREDICTED: rRNA-processing protein UTP23 homolog [Glycine max] gi|356554407|ref|XP_003545538.1| 1
PREDICTED: transducin beta-like protein 3-like [Glycine max] gi|356513431|ref|XP_003525417.1| 2
PREDICTED: WD repeat-containing protein 36-like [Glycine max] gi|356527435|ref|XP_003532316.1| 2
PREDICTED: nucleolar protein 14-like [Cicer arietinum] gi|502122693|ref|XP_004497865.1| 1
PREDICTED: nucleolar protein 14-like [Glycine max] gi|356566913|ref|XP_003551669.1| 1
PREDICTED: probable U3 small nucleolar RNA-associated protein 11-like [Glycine max] gi|356524892|ref|XP_003531062.1| 2
RRNA-processing protein PIN domain protein; TAIR: AT2G34570.1 PIN domain-like family protein; Swiss-Prot: sp|Q9BRU9|UTP23_HUMAN rRNA-processing protein UTP23 homolog; TrEMBL-Plants: tr|A0A0R0G9Y3|A0A0R0G9Y3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0061000 1
RRNA-processing protein PIN domain protein; TAIR: AT2G34570.1 PIN domain-like family protein; Swiss-Prot: sp|Q9BRU9|UTP23_HUMAN rRNA-processing protein UTP23 homolog; TrEMBL-Plants: tr|A0A0R0G9Y3|A0A0R0G9Y3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0061000 1
U3 small nucleolar RNA-associated-like protein; TAIR: AT4G02400.1 U3 ribonucleoprotein (Utp) family protein; Swiss-Prot: sp|P87137|YDM6_SCHPO Uncharacterized protein C57A7.06; TrEMBL-Plants: tr|I1JQM6|I1JQM6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0764400 2
RRNA-processing protein FCF1-like protein; TAIR: AT2G46230.1 PIN domain-like family protein; Swiss-Prot: sp|Q32PD0|FCF1_BOVIN rRNA-processing protein FCF1 homolog; TrEMBL-Plants: tr|I3T9S6|I3T9S6_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0788500 1
RRNA-processing protein FCF1-like protein; TAIR: AT2G46230.1 PIN domain-like family protein; Swiss-Prot: sp|Q32PD0|FCF1_BOVIN rRNA-processing protein FCF1 homolog; TrEMBL-Plants: tr|I3T9S6|I3T9S6_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0788500 1
WD40 repeat-like protein; TAIR: AT4G04940.1 transducin family protein / WD-40 repeat family protein; Swiss-Prot: sp|O14053|UTP21_SCHPO U3 small nucleolar RNA-associated protein 21 homolog; TrEMBL-Plants: tr|A0A0S3TD02|A0A0S3TD02_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0234900 2
RRNA-processing protein FCF1 like; TAIR: AT2G46230.1 PIN domain-like family protein; Swiss-Prot: sp|Q32PD0|FCF1_BOVIN rRNA-processing protein FCF1 homolog; TrEMBL-Plants: tr|I3T9S6|I3T9S6_LOTJA Uncharacterized protein; Found in the gene: LotjaGi3g1v0178700 1
RRNA-processing protein FCF1 like; TAIR: AT2G46230.1 PIN domain-like family protein; Swiss-Prot: sp|Q32PD0|FCF1_BOVIN rRNA-processing protein FCF1 homolog; TrEMBL-Plants: tr|I3T9S6|I3T9S6_LOTJA Uncharacterized protein; Found in the gene: LotjaGi3g1v0178700 1
RRNA-processing protein FCF1-like protein; TAIR: AT1G26530.1 PIN domain-like family protein; Swiss-Prot: sp|Q32PD0|FCF1_BOVIN rRNA-processing protein FCF1 homolog; TrEMBL-Plants: tr|I3T9S6|I3T9S6_LOTJA Uncharacterized protein; Found in the gene: LotjaGi3g1v0178700 1
RRNA-processing protein FCF1 like; TAIR: AT2G46230.1 PIN domain-like family protein; Swiss-Prot: sp|Q32PD0|FCF1_BOVIN rRNA-processing protein FCF1 homolog; TrEMBL-Plants: tr|A0A151TXS1|A0A151TXS1_CAJCA rRNA-processing protein FCF1 isogeny; Found in the gene: LotjaGi3g1v0178700 1
Transducin/WD40 repeat protein; TAIR: AT5G16750.1 Transducin family protein / WD-40 repeat family protein; Swiss-Prot: sp|Q2KJJ5|TBL3_BOVIN Transducin beta-like protein 3; TrEMBL-Plants: tr|I1K010|I1K010_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0233100 2
Transducin/WD40 repeat protein; TAIR: AT5G16750.1 Transducin family protein / WD-40 repeat family protein; Swiss-Prot: sp|Q2KJJ5|TBL3_BOVIN Transducin beta-like protein 3; TrEMBL-Plants: tr|I1K010|I1K010_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0233100 2
Transducin/WD40 repeat protein; TAIR: AT5G16750.1 Transducin family protein / WD-40 repeat family protein; Swiss-Prot: sp|Q2KJJ5|TBL3_BOVIN Transducin beta-like protein 3; TrEMBL-Plants: tr|I1K010|I1K010_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0233100 2
Nucleolar protein 14; TAIR: AT1G69070.2 nucleolar-like protein; Swiss-Prot: sp|P78316|NOP14_HUMAN Nucleolar protein 14; TrEMBL-Plants: tr|I1JB61|I1JB61_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0004800 1
U3 small nucleolar RNA-associated protein 11; TAIR: AT3G60360.1 embryo sac development arrest 14; Swiss-Prot: sp|Q8S1Z1|UTP11_ORYSJ Probable U3 small nucleolar RNA-associated protein 11; TrEMBL-Plants: tr|I3STA5|I3STA5_LOTJA U3 small nucleolar RNA-associated protein 11; Found in the gene: LotjaGi6g1v0229900 2

Co-occuring GO terms 1

A list of co-occurring GO terms within the L. japonicus gene space:

GO term Namespace Name Observations Saturation (%)
Cellular component Small-subunit processome 1 4.00