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Field | Value |
---|---|
Namespace | Molecular function |
Short description | Carotenoid isomerase activity |
Full defintion | Catalysis of the isomerization of poly-cis-carotenoids to all-trans-carotenoids. |
Subterm of |
The relationship of GO:0046608 with other GO terms.
Relationship type | GO terms |
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Is a | |
Regulates | n.a. |
Part of | n.a. |
Positively regulates | n.a. |
Negatively regulates | n.a. |
A force layout showing the ancestor tree for GO:0046608, and its immediate children. If you wish to explore the tree dynamically, please use the GO Explorer.
This table contains additional metadata associated with the GO entry's definition field.
Field | Value |
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PMID | Identification of the carotenoid isomerase provides insight into carotenoid biosynthesis, prolamellar body formation, and photomorphogenesis. Plant Cell. 2002 Feb; 14 (2): 321–32.PMID: 11884677 Carotenoids are essential photoprotective and antioxidant pigments synthesized by all photosynthetic organisms. Most carotenoid biosynthetic enzymes were thought to have evolved independently in bacteria and plants. For example, in bacteria, a single enzyme (CrtI) catalyzes the four desaturations leading from the colorless compound phytoene to the red compound lycopene, whereas plants require two desaturases (phytoene and zeta-carotene desaturases) that are unrelated to the bacterial enzyme. We have demonstrated that carotenoid desaturation in plants requires a third distinct enzyme activity, the carotenoid isomerase (CRTISO), which, unlike phytoene and zeta-carotene desaturases, apparently arose from a progenitor bacterial desaturase. The Arabidopsis CRTISO locus was identified by the partial inhibition of lutein synthesis in light-grown tissue and the accumulation of poly-cis-carotene precursors in dark-grown tissue of crtISO mutants. After positional cloning, enzymatic analysis of CRTISO expressed in Escherichia coli confirmed that the enzyme catalyzes the isomerization of poly-cis-carotenoids to all-trans-carotenoids. Etioplasts of dark-grown crtISO mutants accumulate acyclic poly-cis-carotenoids in place of cyclic all-trans-xanthophylls and also lack prolamellar bodies (PLBs), the lattice of tubular membranes that defines an etioplast. This demonstrates a requirement for carotenoid biosynthesis to form the PLB. The absence of PLBs in crtISO mutants demonstrates a function for this unique structure and carotenoids in facilitating chloroplast development during the first critical days of seedling germination and photomorphogenesis. |
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
Transcript | Name | Description | GO terms | GO count |
---|---|---|---|---|
– | PREDICTED: prolycopene isomerase, chloroplastic-like [Cicer arietinum] gi|502122189|ref|XP_004497623.1| | 2 | ||
– | Carotenoid isomerase; TAIR: AT1G06820.1 carotenoid isomerase; Swiss-Prot: sp|Q8S4R4|CRTSO_SOLLC Prolycopene isomerase, chloroplastic; TrEMBL-Plants: tr|A0A0B2PRP5|A0A0B2PRP5_GLYSO Prolycopene isomerase, chloroplastic; Found in the gene: LotjaGi5g1v0108300 | 2 | ||
– | Carotenoid isomerase; TAIR: AT1G06820.1 carotenoid isomerase; Swiss-Prot: sp|Q8S4R4|CRTSO_SOLLC Prolycopene isomerase, chloroplastic; TrEMBL-Plants: tr|A0A0R0L5D6|A0A0R0L5D6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0108300 | 2 | ||
– | Carotenoid isomerase; TAIR: AT1G06820.1 carotenoid isomerase; Swiss-Prot: sp|Q8S4R4|CRTSO_SOLLC Prolycopene isomerase, chloroplastic; TrEMBL-Plants: tr|A0A0B2PRP5|A0A0B2PRP5_GLYSO Prolycopene isomerase, chloroplastic; Found in the gene: LotjaGi5g1v0108300 | 2 | ||
– | Carotenoid isomerase; TAIR: AT1G06820.1 carotenoid isomerase; Swiss-Prot: sp|Q8S4R4|CRTSO_SOLLC Prolycopene isomerase, chloroplastic; TrEMBL-Plants: tr|I1JGC5|I1JGC5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0108300 | 2 | ||
– | Carotenoid isomerase; TAIR: AT1G06820.1 carotenoid isomerase; Swiss-Prot: sp|Q8S4R4|CRTSO_SOLLC Prolycopene isomerase, chloroplastic; TrEMBL-Plants: tr|A0A0B2PRP5|A0A0B2PRP5_GLYSO Prolycopene isomerase, chloroplastic; Found in the gene: LotjaGi5g1v0108300 | 2 |
A list of co-occurring GO terms within the L. japonicus gene space:
GO term | Namespace | Name | Observations | Saturation (%) |
---|---|---|---|---|
Molecular function | Carotenoid isomerase activity | 1 | 16.67 |